Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DIRECT-INJECTION ANALYSIS OF MITOMYCIN-C IN BIOLOGICAL-FLUIDS BY MULTIDIMENSION HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH A MICELLAR MOBILE-PHASE
Autore:
LIU ZS; LI YM; JIANG SX; CHEN LR;
Indirizzi:
ACAD SINICA,LANZHOU INST CHEM PHYS,DIV ANALYT CHEM LANZHOU 730000 PEOPLES R CHINA
Titolo Testata:
Journal of liquid chromatography & related technologies
fascicolo: 8, volume: 19, anno: 1996,
pagine: 1255 - 1265
SICI:
1082-6076(1996)19:8<1255:DAOMIB>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIRECT SERUM INJECTION; BODY-FLUIDS; CLEANUP; PLASMA; DRUGS; URINE; ASSAY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
Z.S. Liu et al., "DIRECT-INJECTION ANALYSIS OF MITOMYCIN-C IN BIOLOGICAL-FLUIDS BY MULTIDIMENSION HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH A MICELLAR MOBILE-PHASE", Journal of liquid chromatography & related technologies, 19(8), 1996, pp. 1255-1265

Abstract

This paper describes the direct injection analysis of the anticancer drug mitomycin C in biological fluid by an HPLC column switching technique. The first chromatographic column which provides for sample extraction and dean up employs a micellar mobile phase with SDS as the modifier. The second column, coupled on-line to the first, utilizes reverse-phase conditions for analysis. UV detection is employed at 365 nm. Samples from cancer patients and dogs were analyzed. The drug recoveries are 95.9-100.3% with a relative standard deviation of 2.76%. A sample analysis is completed within 15 minutes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 23:31:22