Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE PLASMA-MEMBRANE PROTEIN SNAP-25, BUT NOT SYNTAXIN, IS PRESENT AT PHOTORECEPTOR AND BIPOLAR CELL SYNAPSES IN THE RAT RETINA
Autore:
BRANDSTATTER JH; WASSLE H; BETZ H; MORGANS CW;
Indirizzi:
MAX PLANCK INST HIRNFORSCH,ABT NEUROANAT,DEUTSCHORDENSTR 46 D-60528 FRANKFURT GERMANY MAX PLANCK INST HIRNFORSCH,NEUROCHEM ABT D-60528 FRANKFURT GERMANY
Titolo Testata:
European journal of neuroscience
fascicolo: 4, volume: 8, anno: 1996,
pagine: 823 - 828
SICI:
0953-816X(1996)8:4<823:TPPSBN>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VITRO; FUSION;
Keywords:
RIBBON SYNAPSE; CONVENTIONAL SYNAPSE; SYNAPTIC VESICLE EXOCYTOSIS; PHOTORECEPTOR CELLS; BIPOLAR CELLS; AMACRINE CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
J.H. Brandstatter et al., "THE PLASMA-MEMBRANE PROTEIN SNAP-25, BUT NOT SYNTAXIN, IS PRESENT AT PHOTORECEPTOR AND BIPOLAR CELL SYNAPSES IN THE RAT RETINA", European journal of neuroscience, 8(4), 1996, pp. 823-828

Abstract

The two neuronal plasma membrane proteins synaptosomal associated protein 25 kDa (SNAP-25) and syntaxin form, in current models of synapticvesicle exocytosis, a docking complex on the presynaptic plasma membrane. This docking complex interacts with the integral synaptic vesicleprotein, synaptobrevin, We have examined, in the rat retina, the distribution of SNAP-25 and syntaxin using light and electron microscopic immunocytochemistry, SNAP-25 immunoreactivity was present in the outerand inner nuclear layers at the membranes of photoreceptor and amacrine cell somata, in the outer plexiform layer in the terminals of photoreceptor cells and throughout the inner plexiform layer in the terminals of bipolar and amacrine cells, In contrast, syntaxin immunoreactivity was not found in the terminals of photoreceptor and bipolar cells, but only in the terminals of amacrine cells. Because of the absence ofdetectable syntaxin from the terminals of photoreceptor and bipolar cells, we propose that either a novel syntaxin isoform or a syntaxin-like protein exists at the ribbon synapses formed by these neurons.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 11:11:02