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Titolo:
ONSET OF DIABETES WITH HIGH-TITER ANTI-GAD ANTIBODY AFTER IFN THERAPYFOR CHRONIC HEPATITIS
Autore:
SHIBA T; MORINO Y; TAGAWA K; FUJINO H; UNUMA T;
Indirizzi:
MITSUI MEM HOSP,DEPT INTERNAL MED,CHIYODA KU,1 KANDA IZUNICHO TOKYO 101 JAPAN
Titolo Testata:
Diabetes research and clinical practice
fascicolo: 3, volume: 30, anno: 1995,
pagine: 237 - 241
SICI:
0168-8227(1995)30:3<237:OODWHA>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUTAMIC-ACID DECARBOXYLASE; INTERFERON; MELLITUS; ALPHA;
Keywords:
ANTI-GAD ANTIBODY; IFN; CSII;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
T. Shiba et al., "ONSET OF DIABETES WITH HIGH-TITER ANTI-GAD ANTIBODY AFTER IFN THERAPYFOR CHRONIC HEPATITIS", Diabetes research and clinical practice, 30(3), 1995, pp. 237-241

Abstract

A case of hyperglycemia induced by the injection of interferon-cr wasexperienced in our hospital. This patient showed a sustained high titer of anti-GAD antibody after the onset of diabetes, suggesting that the involvement of immunological disturbance by IFN induces the onset of the disease. However, the susceptibility and the response of the immune system differs from patient to patient, and only limited destruction of beta-cells in the islet of Langerhans and normalization of glucose tolerance by CSII was induced in this patient.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 18:42:33