Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
POTENTIAL CARDIOEMBOLIC SOURCES OF STROKE IN PATIENTS LESS-THAN-60 YEARS OF AGE
Autore:
NIGHOGHOSSIAN N; PERINETTI M; BARTHELET M; ADELEINE P; TROUILLAS P;
Indirizzi:
HOP NEUROL,SERV NEUROL PR TROUILLAS URGENCES NEUROVASC,59 BD PINEL F-69003 LYON FRANCE HOP NEUROL,CTR RECH ATAXIE F-69003 LYON FRANCE SERV NEUROL & URGENCES CEREBROVASC PR PAUL TROUIL LYON FRANCE HOP CARDIOL,LAB ECOCARDIOG DOPPLER LYON FRANCE UFR ALEXIS CARREL,LAB INFORMAT MED LYON FRANCE
Titolo Testata:
European heart journal
fascicolo: 4, volume: 17, anno: 1996,
pagine: 590 - 594
SICI:
0195-668X(1996)17:4<590:PCSOSI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
ATRIAL SEPTAL ANEURYSM; MITRAL-VALVE PROLAPSE; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; PREVALENCE; INFARCTS; EMBOLISM; EVENTS;
Keywords:
ATRIAL SEPTAL ANEURYSM; PATENT FORAMEN OVALE; CRYPTOGENIC STROKE; TRANSESOPHAGEAL ECHOCARDIOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
N. Nighoghossian et al., "POTENTIAL CARDIOEMBOLIC SOURCES OF STROKE IN PATIENTS LESS-THAN-60 YEARS OF AGE", European heart journal, 17(4), 1996, pp. 590-594

Abstract

Minor potential cardioembolic sources of stroke such as atrial septalaneurysm or patent foramen ovale are important risk factors for cryptogenic stroke. We aimed to determine the prevalence of these abnormalities through an exhaustive aetiological work-up. One hundred and eighteen stroke patients under 60 years of age, who had no evidence of a significant cardiac source of embolism, were classified into four groupsfollowing transoesophageal echocardiography and assessment of cervical arteries. Group A comprised 30 patients (25.4%) who had an arteriopathy, probably related to stroke without ally cardiac abnormality; group B, had only a potential cardiac source; group C, nine (7.6%) had an obvious arterial source of stroke and incidental cardiac abnormalities; group D, 30 (25.4%) had neither cardiac or arterial source. Data were analysed with the Chi-square test to compare risk factors between groups, and variance analysis was used to compare age between groups. Significance was assessed as P<0.05. Fisher's exact test was used to test the association between arterial septal aneurysm and patent foramen ovale. In groups B and D atrial septal aneurysm represented 56.8% of the cardiac abnormalities and was diagnosed 35.4% of the 79 patients who had an unexplained stroke, and a patent foramen ovale was found in 34.1% of the patients. According to Fisher's exact test, atrial septal aneurysm was significantly associated with patent foramen ovale (P much less than 0.001). On this basis, one fourth of the patients might besaid to have had a truly cryptogenic stroke as the aetiological work-up failed to demonstrate any source of stroke. Comparison between groups showed that in 23% of the patients in whom an arterial source was detected, there was also a potential cardioembolic source (group C), vs62% in patients who had no arterial source (groups B and D) (P=0.0007). Our study confirmed the strong association between atrial septal aneurysm, patent foramen ovale and stroke. Although there was a lower incidence of cardiac risk factors for stroke in patients who had cervical artery disease, we suggest that all patients who have a stroke without evidence of a major cardiac source should undergo transoesophageal echocardiography, in order to ensure a better prevention.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 13:40:17