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Titolo:
IS THE SONOGRAPHIC DEGREE OF BLOOD-SUPPLY A NEW PROGNOSTIC FACTOR
Autore:
SOHN C; THIEL C; BAUDENDISTEL A; KAUFMANN M; BASTERT G;
Indirizzi:
UNIV HEIDELBERG,FRAUENKLIN,VOSSSTR 9 D-69115 HEIDELBERG GERMANY UNIV HEIDELBERG,DEPT PRENATAL & GYNECOL ULTRASOUND DIAG & THERAPY,CLIN OBSTET & GYNECOL W-6900 HEIDELBERG GERMANY
Titolo Testata:
Breast
fascicolo: 2, volume: 5, anno: 1996,
pagine: 110 - 112
SICI:
0960-9776(1996)5:2<110:ITSDOB>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
BREAST-TUMORS; FLOW;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
C. Sohn et al., "IS THE SONOGRAPHIC DEGREE OF BLOOD-SUPPLY A NEW PROGNOSTIC FACTOR", Breast, 5(2), 1996, pp. 110-112

Abstract

The aim of the present study was to investigate the relationship between the biological behaviour of breast cancer and ultrasonographicallydetected blood flow. The investigations were carried out with a prototype colour ultrasound unit - CSA Acoustic Imaging, Phoenix, MEM colour technique. This machine identifies very low blood flow velocities that are not detected by conventional Doppler methodology. Blood flow was assessed on the visual colour information obtained (class I low, blood flow, single colour pixels - class III, high blood flow, several colour areas). Although the subjectivity of this classification is a disadvantage there was no intra-observer variation in this study. In 119 patients with invasive ductal breast carcinomas, there was a close correlation between the degree of blood flow and tumour size, lymph node status, S-fraction, ploidy and receptor status. Approximately 91% of patients with class I blood flow had negative lymph nodes whereas 81% of women with class III blood flow had lymph node metastases. Low flow was associated with diploid tumour cells, an S-fraction < 5.0 and positive hormone receptor status. Aneuploid tumour cells, high S-fraction and negative hormone receptor status correlated strongly with high blood flow. This correlation between established prognostic factors and ultrasonographic assessment of blood flow indicates that blood flow in a tumour may have prognostic value and further studies are indicated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 10:27:22