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Titolo:
EPIDEMIOLOGY OF INFECTION BY NONTUBERCULOUS MYCOBACTERIA
Autore:
FALKINHAM JO;
Indirizzi:
VIRGINIA TECH,DEPT BIOL BLACKSBURG VA 24061 VIRGINIA POLYTECH INST & STATE UNIV,DEPT BIOL BLACKSBURG VA 24061
Titolo Testata:
Clinical microbiology reviews
fascicolo: 2, volume: 9, anno: 1996,
pagine: 177 -
SICI:
0893-8512(1996)9:2<177:EOIBNM>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACQUIRED-IMMUNODEFICIENCY-SYNDROME; AVIUM COMPLEX INFECTION; RAPIDLY GROWING MYCOBACTERIA; IMMUNE-DEFICIENCY-SYNDROME; INTERNATIONAL-WORKING-GROUP; INFLAMMATORY BOWEL-DISEASE; INTRACELLULARE-SCROFULACEUM COMPLEX; POTENTIALLY PATHOGENIC MYCOBACTERIA; DEOXYRIBONUCLEIC-ACID RELATEDNESS; MULTILOCUS ENZYME ELECTROPHORESIS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
575
Recensione:
Indirizzi per estratti:
Citazione:
J.O. Falkinham, "EPIDEMIOLOGY OF INFECTION BY NONTUBERCULOUS MYCOBACTERIA", Clinical microbiology reviews, 9(2), 1996, pp. 177

Abstract

The past 10 years have seen enormous increases in the number of nontuberculous mycobacterial infections, principally in patients with AIDS. Today, there is heightened awareness of the importance of nontuberculous mycobacterial infections. In addition to the increase in the number of infections with known mycobacteria (e.g, Mycobacterium avium), new species (e.g., Mycobacterium genavense) have been identified some bynonconventional methods. For the most part, nontuberculous mycobacteria are opportunistic pathogens whose normal habitat is natural (e.g., livers, swamps, and soils) and human-influenced (e.g, drinking water) environments. Focus has been on identification of sources and routes of transmission. Sources have been identified for some (e.g, M. avium and Mycobacterium xenopi) but not others (e.g, Mycobacterium haemophilum). Physiological studies have led to descriptions of the ecology and epidemiology for some species. Some grow in natural or potable water. All strains tested have been resistant to standard methods of disinfection. Consequently, they are found in drinking water. Characteristics that enhance environmental survival may also promote survival in infected animals Tools for genetic analysis of nontuberculous mycobacteria (e.g, PCR) have led to identification of antibiotic resistance genes and to development of molecular markers for epidemiological studies. Molecular markers have confirmed the wide heterogeneity of natural mycobacterial populations and have been used to show the genetic identity of environmental and patient isolates.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 04:00:34