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Titolo:
MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY IN ACUTE MYOCARDIAL-INFARCTION -PATHOPHYSIOLOGICAL BACKGROUND AND CLINICAL-APPLICATIONS
Autore:
ILICETO S; MARANGELLI V; MARCHESE A; AMICO A; GALIUTO L; RIZZON P;
Indirizzi:
UNIV CAGLIARI,INST CARDIOL,VIA S GIORGIO 12 I-09124 CAGLIARI ITALY UNIV BARI,INST CARDIOL BARI ITALY
Titolo Testata:
European heart journal
fascicolo: 3, volume: 17, anno: 1996,
pagine: 344 - 353
SICI:
0195-668X(1996)17:3<344:MCEIAM>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
TWO-DIMENSIONAL ECHOCARDIOGRAPHY; COLLATERAL BLOOD-FLOW; NO-REFLOW PHENOMENON; POSITRON EMISSION TOMOGRAPHY; FUNCTIONAL BORDER ZONE; LEFT-VENTRICULAR AREA; CORONARY-OCCLUSION; ISCHEMIC MYOCARDIUM; SONICATED ALBUMIN; CONSCIOUS DOG;
Keywords:
MICROCIRCULATION; MYOCARDIAL VIABILITY; MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY; MYOCARDIAL INFARCTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
69
Recensione:
Indirizzi per estratti:
Citazione:
S. Iliceto et al., "MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY IN ACUTE MYOCARDIAL-INFARCTION -PATHOPHYSIOLOGICAL BACKGROUND AND CLINICAL-APPLICATIONS", European heart journal, 17(3), 1996, pp. 344-353

Abstract

Myocardial contrast echocardiography is a technique used in experimental and clinical settings in order to visualize the pattern of intramyocardial perfusion. In the acute phase of myocardial infarction, regional absence of flow during myocardial contrast echocardiography delineates the area at risk of necrosis, while the definitive non-perfused area expresses infarct size. Reopening the infarct-related artery, which may be achieved spontaneously by thrombolysis or percutaneous transluminal coronary angioplasty, is not a reliable indicator of intramyocardial reperfusion. If myocardial ischaemia due to coronary occlusion has been sufficiently prolonged and severe, not only myocyte viability,but also microvascular integrity is lost. Myocardial contrast echocardiography, using intracoronary injection of sonicated contrast medium,gives information about microvascular integrity and the effective presence of intramyocardial reflow. Anatomical integrity of microvasculature does not necessarily imply preserved function, and thus the microvessel vasodilating reserve may also be impaired. Myocardial contrast echocardiography has the potential to assess alterations in microvascular Function, showing, in the myocardial area with reduced coronary reserve, a relatively reduced increase in echocontrast signal intensity when an intravenous vasodilator agent is administered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 05:30:22