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Titolo:
CLINICAL-APPLICATION OF CHEMILUMINESCENT IMMUNOASSAY FOR THYROID-STIMULATING HORMONE, FREE-T-4 AND INTACT-PARATHYROID HORMONE
Autore:
CHEN CK; TSAI KS;
Indirizzi:
NATL TAIWAN UNIV HOSP,DEPT LAB MED,7 CHUNG SHAN S RD TAIPEI TAIWAN NATL TAIWAN UNIV HOSP,DEPT LAB MED TAIPEI TAIWAN
Titolo Testata:
Journal of the Formosan Medical Association
fascicolo: 3, volume: 95, anno: 1996,
pagine: 197 - 202
SICI:
0929-6646(1996)95:3<197:COCIFT>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOCKED ANALOG ASSAYS; CHEMICAL BLOCKERS; THYROTROPIN ASSAY; BINDING GLOBULIN; FREE THYRONINES; T4 ANALOG; DIAGNOSIS; ALBUMIN;
Keywords:
THYROID STIMULATING HORMONE; FREE THYROXINE; INTACT PARATHYROID HORMONE; CHEMILUMINESCENT IMMUNOASSAY; IMMUNORADIOMETRIC IMMUNOASSAY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
C.K. Chen e K.S. Tsai, "CLINICAL-APPLICATION OF CHEMILUMINESCENT IMMUNOASSAY FOR THYROID-STIMULATING HORMONE, FREE-T-4 AND INTACT-PARATHYROID HORMONE", Journal of the Formosan Medical Association, 95(3), 1996, pp. 197-202

Abstract

To meet the demands of clinical practice, rapid, sensitive and specific laboratory tests are essential. We evaluated the performance of a newer generation of chemiluminescent immunoassay (CLIA) system (Immulite, Diagnostic Products Corp, Los Angeles, CA, USA) and compared it with a popular immunoradiometric immunoassay (IRMA) system. The data of 158 patients whose thyroid function was assessed and that of another 158 patients whose parathyroid function was assessed were analyzed. The thyroid stimulating hormone (TSH) CLIA is an ultrasensitive TSH (us-TSH) assay that provides more detailed, reliable results for low TSH concentrations than TSH IRMA. Coupled with die free-T-4 assay, the us-TSHassay enhances the ability to detect and monitor the status of thyroid dysfunction. Intact-parathyroid hormone (PTH) CLIA can detect lower serum intact-PTH levels, is more sensitive and is as reliable as IRMA. Combined with serum calcium levels and clinical conditions, it provedefficient and discriminated reliably between hypercalcemia associatedwith malignancy and that of hyperparathyroidism.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 01:04:08