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Titolo:
SURFACTANT - CURRENT AND POTENTIAL THERAPEUTIC APPLICATION IN INFANTSAND ADULTS
Autore:
LEWIS J; VELDHUIZEN RAW;
Indirizzi:
UNIV WESTERN ONTARIO,ST JOSEPHS HLTH CTR,LAWSON RES INST,DEPT MED,268GROSVENOR ST LONDON ON N6A 4V2 CANADA
Titolo Testata:
Journal of aerosol medicine
fascicolo: 1, volume: 9, anno: 1996,
pagine: 143 - 154
SICI:
0894-2684(1996)9:1<143:S-CAPT>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS SYNDROME; PULMONARY SURFACTANT; LUNG INJURY; PROTEIN-A; ALVEOLAR MACROPHAGES; REPLACEMENT THERAPY; WEEKS GESTATION; RAT LUNG; SUBFRACTIONS; METABOLISM;
Keywords:
SURFACTANT SUPPLEMENTATION; ACUTE LUNG INJURY; ARDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
J. Lewis e R.A.W. Veldhuizen, "SURFACTANT - CURRENT AND POTENTIAL THERAPEUTIC APPLICATION IN INFANTSAND ADULTS", Journal of aerosol medicine, 9(1), 1996, pp. 143-154

Abstract

Exogenous surfactant administration is currently being evaluated for the Acute Respiratory Distress Syndrome (ARDS). Although surfactant supplementation is now a routine therapy for babies born with neonatal RDS, this treatment modality for adults does not appear to result in a predictable improvement in lung function as is noted in neonates. Thisarticle will review the basic abnormalities of the surfactant system in patients with ARDS and contrast them with the primary surfactant deficient state of nRDS. Various factors that have been shown to influence an individual's response to exogenous surfactant will the be outlined. Finally, potential treatment approaces for patiens with ARDS utilizing exogenous surfactant mill be proposed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:31:32