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Titolo:
A NOVEL TETRACYCLINE-RESISTANT DETERMINANT, TET(U), IS ENCODED ON THEPLASMID PKQ10 IN ENTEROCOCCUS-FAECIUM
Autore:
RIDENHOUR MB; FLETCHER HM; MORTENSEN JE; DANEOMOORE L;
Indirizzi:
TEMPLE UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL PHILADELPHIA PA 19140 TEMPLE UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL PHILADELPHIA PA 19140 TEMPLE UNIV HOSP & MED SCH,DEPT PEDIAT PHILADELPHIA PA 19140 VIRGINIA COMMONWEALTH UNIV,DEPT MICROBIOL & IMMUNOL RICHMOND VA 23298 ST CHRISTOPHERS HOSP CHILDREN,DEPT LABS PHILADELPHIA PA 19134
Titolo Testata:
Plasmid
fascicolo: 2, volume: 35, anno: 1996,
pagine: 71 - 80
SICI:
0147-619X(1996)35:2<71:ANTDTI>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPLETE NUCLEOTIDE-SEQUENCE; LACTOBACILLUS-PLANTARUM; CRYPTIC PLASMID; GENE; PROTEIN; CLONING; TN916; TETM; DNA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
M.B. Ridenhour et al., "A NOVEL TETRACYCLINE-RESISTANT DETERMINANT, TET(U), IS ENCODED ON THEPLASMID PKQ10 IN ENTEROCOCCUS-FAECIUM", Plasmid, 35(2), 1996, pp. 71-80

Abstract

Nine tetracycline (Tc)-resistant clinical isolates of Enterococcus faecium were screened for plasmid content using agarose gel electrophoresis. pKQ10, a 1.9-kb plasmid carrying a novel Tc resistance determinant, was isolated from one of the isolates. The nucleotide sequence of this plasmid revealed an open reading frame corresponding to an 11.8-kDa protein and containing 105 amino acid residues. There was some limited similarity between this protein and tet(M), ret(O), ter(Q), tet(S),terB(P), and otr(A), which overlapped, but did not include, the consensus GTP-binding sequences. The low-level, Tc-resistant determinant ofpKQ10, named ret(U), does not appear to correspond to any other knownTc resistance determinant. (C) 1996 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:21:51