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Titolo:
PULMONARY-FUNCTION AND EXERCISE CAPACITY AFTER LUNG RESECTION
Autore:
BOLLIGER CT; JORDAN P; SOLER M; STULZ P; TAMM M; WYSER C; GONON M; PERRUCHOUD AP;
Indirizzi:
UNIV BASEL HOSP,DEPT INTERNAL MED,DIV PNEUMOL,PETERSGRABEN 4 CH-4031 BASEL SWITZERLAND UNIV BASEL HOSP,CARDIOTHORAC UNIT,DEPT SURG CH-4031 BASEL SWITZERLAND
Titolo Testata:
The European respiratory journal
fascicolo: 3, volume: 9, anno: 1996,
pagine: 415 - 421
SICI:
0903-1936(1996)9:3<415:PAECAL>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
PREOPERATIVE ASSESSMENT; PNEUMONECTOMY; PREDICTION; LOBECTOMY; CARCINOMA;
Keywords:
EXERCISE CAPACITY; LUNG RESECTION; PULMONARY FUNCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
C.T. Bolliger et al., "PULMONARY-FUNCTION AND EXERCISE CAPACITY AFTER LUNG RESECTION", The European respiratory journal, 9(3), 1996, pp. 415-421

Abstract

The influence of pulmonary resection on functional capacity can be assessed in different ways, The aim of this study was to compare the effect of lobectomy and pneumonectomy on pulmonary function tests (PFT), exercise capacity and perception of symptoms. Sixty eight patients underwent functional assessment with PFT and exercise testing before (Preop), and 3 and 6 months after lung resection, In 50 (36 males and 14 females; mean age 61 yrs) a lobectomy was performed and in 18 (13 malesand 5 females; mean age 59 yrs) a pneumonectomy was performed. Three months after lobectomy, forced vital capacity (FVC), forced expiratoryvolume in one second (FEV(1)), total lung capacity (TLC), transfer factor of the lungs for carbon monoxide (TL,CO) and maximal oxygen uptake (V'O-2,max) were significantly lower than Preop values, increasing significantly from 3 to 6 months after resection, Three months after pneumonectomy, all parameters were significantly lower than Preop valuesand significantly lower than postlobectomy values and did not recoverfrom 3 to 6 months after resection, At 6 months after resection significant deficits persisted in comparison with Preop: for FVC 7% and 36%, FEV(1) 9% and 34%, TLC 10% and 33% for lobectomy and pneumonectomy, respectively; and V'O-2,max 20% after pneumonectomy only, Exercise waslimited by leg muscle fatigue in 53% of all patients at Preop. This was not altered by lobectomy, but there was a switch to dyspnoea as theLimiting factor after pneumonectomy (61%, of patients at 3 months and50% at 6 months after resection), Furthermore, pneumonectomy comparedto lobectomy led to a significantly smaller breathing reserve (mean+/-SD) (28+/-13 vs 37+/-16% at 3 months; and 24+/-11% vs 33+/-12% at 6 months post resection) and lower arterial oxygen tension at peak exercise 10.1+/-1.5 vs 11.5+/-1.6 kPa (76+/-11 vs 86+/-12 mmHg) at 3 months;10.1+/-1.3 vs 11.3+/-1.6 kPa (76+/-10 vs 85+/-12 mmHg) at 6 months postresection, We conclude that measurements of conventional pulmonary function tests alone overestimate the decrease in functional capacity after lung resection, Exercise capacity after lobectomy is unchanged, whereas pneumonectomy leads to a 20% decrease, probably due to the reduced area of gas exchange. (C)ER Journals Ltd 1996.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 15:54:26