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Titolo:
ANALYSIS OF THE NUCLEOTIDE-SEQUENCE OF 23.8 KBP FROM THE LEFT TERMINUS OF THE GENOME OF VARIOLA MAJOR VIRUS-STRAIN INDIA-1967
Autore:
SHCHELKUNOV SN; TOTMENIN AV; SANDAKHCHIEV LS;
Indirizzi:
STATE RES CTR VIROL & BIOTECHNOL VECTOR,INST MOLEC BIOL KOLTSOV 633159 RUSSIA
Titolo Testata:
Virus research
fascicolo: 2, volume: 40, anno: 1996,
pagine: 169 - 183
SICI:
0168-1702(1996)40:2<169:AOTNO2>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSFORMING GROWTH-FACTOR; SERINE PROTEASE INHIBITOR; COMPLEMENT CONTROL PROTEINS; RABBIT FIBROMA VIRUS; HOST RANGE GENES; VACCINIA VIRUS; FACTOR-ALPHA; ECTROMELIA VIRUS; SECRETED PROTEIN; INFECTED-CELLS;
Keywords:
POXVIRUS; VARIOLA VIRUS; GENOME DNA SEQUENCE; SEQUENCE ANALYSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
82
Recensione:
Indirizzi per estratti:
Citazione:
S.N. Shchelkunov et al., "ANALYSIS OF THE NUCLEOTIDE-SEQUENCE OF 23.8 KBP FROM THE LEFT TERMINUS OF THE GENOME OF VARIOLA MAJOR VIRUS-STRAIN INDIA-1967", Virus research, 40(2), 1996, pp. 169-183

Abstract

Sequencing and computer analysis of the nucleotide sequence of variola major virus strain India-1967 (VAR-MD) DNA segment (23 786 bp) covering the left variable region of the viral genome has been carried out. Twenty-nine potential open reading frames were identified. Structure-function organization of the VAR-IND DNA segment was compared with previously reported sequences from analogous genome regions of vaccinia virus strains Copenhagen (VAC-COP) and Western Reserve (VAC-WR). Multiple structural differences between the VAR-IND and genome regions were analysed and both VAC-COP and VAC-WR have been found. Possible molecular factors of virulence, virus host range genes as well as differencesrevealed in the structure of these genes of VAR and VAC will be discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 09:42:23