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Titolo:
CORTICAL SURFACE MODELING REVEALS GROSS MORPHOMETRIC CORRELATES OF INDIVIDUAL-DIFFERENCES
Autore:
LOFTUS WC; TRAMO MJ; GAZZANIGA MS;
Indirizzi:
UNIV CALIF DAVIS,CTR NEUROSCI DAVIS CA 95616 HARVARD UNIV,SCH MED,DEPT NEUROBIOL BOSTON MA 02115 MASSACHUSETTS GEN HOSP,NEUROL SERV BOSTON MA 02115
Titolo Testata:
Human brain mapping
fascicolo: 4, volume: 3, anno: 1995,
pagine: 257 - 270
SICI:
1065-9471(1995)3:4<257:CSMRGM>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLANUM TEMPORALE ASYMMETRY; DEVELOPMENTAL DYSLEXIA; CEREBRAL ASYMMETRY; MONOZYGOTIC TWINS; SCHIZOPHRENIA; BRAIN; RECONSTRUCTION; ABNORMALITIES; LOCALIZATION; HANDEDNESS;
Keywords:
CEREBRAL CORTEX; CEREBRAL HEMISPHERES; TELENCEPHALON; MAGNETIC RESONANCE IMAGING; QUANTITATIVE NEUROANATOMY; MONOZYGOTIC TWINS; SEX DIFFERENCES; DYSLEXIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
78
Recensione:
Indirizzi per estratti:
Citazione:
W.C. Loftus et al., "CORTICAL SURFACE MODELING REVEALS GROSS MORPHOMETRIC CORRELATES OF INDIVIDUAL-DIFFERENCES", Human brain mapping, 3(4), 1995, pp. 257-270

Abstract

Advances in human neurobiology are now made possible through methods which combine structural magnetic resonance imaging (MRI), three-dimensional reconstruction, and statistical analysis. MRI-based reconstruction enables the in vivo quantification of regional cortical surface area (rCSA) while inter-group comparisons uncover relationships of cortical morphometry with genotype, sex, and developmental abnormalities. In studies on normals we have found strong associations between the rCSA of monozygotic twins as compared to unrelated pairings. Further analysis of this data uncovered significant differences between the male and female twins in left hemisphere rCSA. When these methods were applied to brains of dyslexic subjects and controls, we identified a pattern of differences involving all major subdivisions of both hemispheres. Taken together, these techniques can illuminate structure-function issues in both normal and diseased brains. (C) 1996 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 13:10:45