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Titolo:
24 HOUR HEART PERIOD VARIABILITY IN SYSTEMIC-SCLEROSIS
Autore:
MORELLI S; PICCIRILLO G; FIMOGNARI F; SGRECCIA A; FERRANTE L; MORABITO G; DEMARZIO P; VALESINI G; MARIGLIANO V;
Indirizzi:
POLICLIN UMBERTO 1,IST CLIN MED 1,VIALE POLICLIN I-00161 ROME ITALY UNIV ROMA LA SAPIENZA,IST CLIN MED 1 ROME ITALY
Titolo Testata:
Journal of rheumatology
fascicolo: 4, volume: 23, anno: 1996,
pagine: 643 - 645
SICI:
0315-162X(1996)23:4<643:2HHPVI>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIAC PARASYMPATHETIC ACTIVITY; POWER SPECTRAL-ANALYSIS; MYOCARDIAL-INFARCTION; FREQUENCY-DOMAIN; NEUROPATHY;
Keywords:
SYSTEMIC SCLEROSIS; HEART RATE VARIABILITY; AUTONOMIC NERVOUS SYSTEM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
S. Morelli et al., "24 HOUR HEART PERIOD VARIABILITY IN SYSTEMIC-SCLEROSIS", Journal of rheumatology, 23(4), 1996, pp. 643-645

Abstract

Objective. In patients with systemic sclerosis (SSc), an autonomic dysfunction has been implicated in the pathogenesis of Raynaud's phenomenon and gastrointestinal symptoms. To evaluate cardiovascular autonomic function we analyzed the heart rate variability (HRV) on 24 h electrocardiogram recordings. Methods. In 50 patients diagnosed with SSc and24 control subjects HRV was analyzed for both frequency and time domain. Results. Frequency domain analysis showed reduction of low frequency and high frequency values in the patients with SSc compared to controls (5.52 +/- 0.74 vs 6.04 +/- 0.78 In (ms(2)), p = 0.007; and 4.17 +/- 0.97 vs 4.14 +/- 0.97 In(ms(2)), p = 0.021, respectively). Analysisin the time domain showed no significant differences in any variable between groups. There were no significant differences between the diffuse and the limited form of SSc, Number of ventricular ectopic beats, prevalence of frequent ventricular ectopy, and supraventricular tachycardia episodes were increased in the patients with SSc compared to controls. Conclusion. Spectral analysis of heart period variability suggests cardiovascular autonomic dysfunction in patients with SSc. Better understanding of this complication could help delineate new strategiesfor the treatment of SSc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 22:34:51