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Titolo:
CLINICAL-APPLICATIONS OF GENETIC REARRANGEMENTS IN CANCER
Autore:
SHEER D; SQUIRE J;
Indirizzi:
IMPERIAL CANC RES FUND,44 LINCOLNS INN FIELDS,POB 123 LONDON WC2A 3PXENGLAND UNIV TORONTO,DEPT PATHOL TORONTO ON M5G 1X8 CANADA UNIV TORONTO,HOSP SICK CHILDREN TORONTO ON M5G 1X8 CANADA
Titolo Testata:
Seminars in cancer biology
fascicolo: 1, volume: 7, anno: 1996,
pagine: 25 - 32
SICI:
1044-579X(1996)7:1<25:COGRIC>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE LYMPHOBLASTIC-LEUKEMIA; POLYMERASE CHAIN-REACTION; MINIMAL RESIDUAL DISEASE; INDUCTION THERAPY; TRANSLOCATION; DIAGNOSIS; PREDICTOR; RELAPSE;
Keywords:
GENETIC ABERRATIONS; DIAGNOSIS; PROGNOSIS; RESIDUAL DISEASE; THERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
D. Sheer e J. Squire, "CLINICAL-APPLICATIONS OF GENETIC REARRANGEMENTS IN CANCER", Seminars in cancer biology, 7(1), 1996, pp. 25-32

Abstract

Genetic aberrations in cancer cells can be of immediate relevance to the patient. They enable definitive diagnoses to be reached and sub-classification of certain tumour types into good or bad prognostic groups, information which can influence therapy. These aberrations can alsobe used as tumour markers for monitoring the response to therapy. Major technological advances in the last few years have facilitated theseapplications in the routine clinical setting and encouraged searches for new genetic markers. As the genes directly affected are identifiedand their roles in tumorigenesis elucidated, they are likely to provide novel targets for therapeutic intervention.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 11:46:31