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Titolo:
CRYOPRESERVED ARTERIAL ALLOGRAFTS FOR LIMB SALVAGE IN THE ABSENCE OF SUITABLE SAPHENOUS-VEIN - 2-YEAR RESULTS IN 20 CASES
Autore:
GOURNIER JP; FAVRE JP; GAY JL; BARRAL X;
Indirizzi:
CHU ST ETIENNE,HOP NORD,SERV CHIRURG CARDIOVASC F-42055 ST ETIENNE FRANCE
Titolo Testata:
Annals of vascular surgery
, volume: 9, anno: 1995, supplemento:, S
pagine: 7 - 14
SICI:
0890-5096(1995)9:<7:CAAFLS>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOWER-EXTREMITY ISCHEMIA; VENOUS ALLOGRAFTS; BYPASS GRAFTS; POLYTETRAFLUOROETHYLENE GRAFTS; VASCULAR RECONSTRUCTION; AUTOGENOUS VEIN; TERM; EXPERIENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
J.P. Gournier et al., "CRYOPRESERVED ARTERIAL ALLOGRAFTS FOR LIMB SALVAGE IN THE ABSENCE OF SUITABLE SAPHENOUS-VEIN - 2-YEAR RESULTS IN 20 CASES", Annals of vascular surgery, 9, 1995, pp. 7-14

Abstract

From January 1992 to November 1992, 20 cryopreserved arterial allografts were used as below-knee bypasses for repeated limb salvage in 18 patients lacking saphenous vein grafts. Arteries were obtained during multiorgan harvesting. A scheduled program of cryopreservation with 15%dimethylsulfoxide was used. Mean storage period was 37 days. All cases were matched for blood group compatibility. Patency was checked at 10 and 90 days and twice a year thereafter. Conventional arteriography was routinely performed 3 months postoperatively. Average follow-up was 26.8 months for the 18 patients and 20.8 months for the 20 bypass grafts. No patients were lost to follow-up. Aneurysmal dilatation developed in one graft, which was replaced by another homograft. During follow-up 10 grafts occluded: five once, four twice, and one four times. These 10 grafts underwent a total of 16 reinterventions. Thrombectomy with angioplasty was performed 15 times and graft replacement once because of proximal and distal arterial deterioration. Primary actuarial patency was 68% at 1 year and 42% at 2 years. Secondary actuarial patency was 89% at 1 year and 72% at 2 years. Preliminary results of cryopreserved arterial allografts for repeated limb salvage in the absence of available saphenous veins are encouraging. Further studies are needed to determine the long-term deterioration rate of cryopreserved arterial allografts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 20:09:30