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Titolo:
MAGNESIUM-SULFATE ENHANCES RESIDUAL NEUROMUSCULAR BLOCK INDUCED BY VECURONIUM
Autore:
FUCHSBUDER T; TASSONYI E;
Indirizzi:
UNIV HOSP GENEVA,DEPT ANAESTHESIOL,RUE MICHELIDU CREST 24 CH-1211 GENEVA 14 SWITZERLAND
Titolo Testata:
British Journal of Anaesthesia
fascicolo: 4, volume: 76, anno: 1996,
pagine: 565 - 566
SICI:
0007-0912(1996)76:4<565:MERNBI>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANESTHESIA;
Keywords:
NEUROMUSCULAR BLOCK, VECURONIUM; NEUROMUSCULAR BLOCK, RECOVERY; IONS, MAGNESIUM; MEASUREMENT TECHNIQUES, ELECTROMYOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
5
Recensione:
Indirizzi per estratti:
Citazione:
T. Fuchsbuder e E. Tassonyi, "MAGNESIUM-SULFATE ENHANCES RESIDUAL NEUROMUSCULAR BLOCK INDUCED BY VECURONIUM", British Journal of Anaesthesia, 76(4), 1996, pp. 565-566

Abstract

Magnesium sulphate (MgSO4) is currently used for haemodynamic controlduring anaesthesia and the early postoperative period. We have investigated the effect of this treatment on residual neuromuscular block after administration of vecuronium. Twenty adult patients were allocatedrandomly to one of two groups to receive MgSO4 60 mg kg(-1) either atrecovery from vecuronium block to a train-of-four (TOF) ratio of 0.7,or 1 h after recovery to a TOF ratio of 0.7. Neuromuscular transmission was monitored using electromyography and TOF stimulation. MgSO4 caused rapid and profound recurarization in all 20 patients. MgSO4 decreased the amount of acetylcholine released at the motor nerve terminal and thus may lead to recurarization in patients previously exposed to neuromuscular blocking agents.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 08:46:40