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Titolo:
DIURNAL-VARIATION OF PLASMA-CORTISOL AND HOMOVANILLIC-ACID IN HEALTHY-SUBJECTS
Autore:
POSENER JA; SCHILDKRAUT JJ; SAMSON JA; SCHATZBERG AF;
Indirizzi:
MCLEAN HOSP,115 MILL ST BELMONT MA 02178 MASSACHUSETTS MENTAL HLTH CTR BOSTON MA 02115 BRIGHAM & WOMENS HOSP,DIV PSYCHIAT BOSTON MA 02115 HARVARD UNIV,SCH MED BOSTON MA 00000 STANFORD UNIV,SCH MED,DEPT PSYCHIAT & BEHAV SCI STANFORD CA 00000
Titolo Testata:
Psychoneuroendocrinology
fascicolo: 1, volume: 21, anno: 1996,
pagine: 33 - 38
SICI:
0306-4530(1996)21:1<33:DOPAHI>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; ELECTROCHEMICAL DETECTION; CATECHOLAMINES; SCHIZOPHRENIA; DEPRESSION; DOPAMINE; CSF;
Keywords:
GLUCOCORTICOIDS; HYDROCORTISONE; DOPAMINE; HOMOVANILLIC ACID; DEPRESSION; PSYCHOTIC DISORDERS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Posener et al., "DIURNAL-VARIATION OF PLASMA-CORTISOL AND HOMOVANILLIC-ACID IN HEALTHY-SUBJECTS", Psychoneuroendocrinology, 21(1), 1996, pp. 33-38

Abstract

We investigated the relationship between plasma levels of cortisol, the dopamine metabolite homovanillic acid (HVA) and norepinephrine in healthy human subjects. Plasma cortisol and HVA levels were measured at0800h, and in an integrated sampling procedure involving samples every 15 min between 1300 and 1600h. Plasma norepinephrine was measured at0800 and 1300h. Cortisol, HVA and norepinephrine indices did not showsignificant correlations with each other. Both cortisol and HVA showed significant decreases over time. Longitudinal Random Effects (LRE) models were used to test whether individual cortisol and HVA curves over time were correlated; significant corelations were not found with this procedure. While significant correlations between cortisol and catecholamine indices have been reported in depressed patients, our results do not suggest such correlations in healthy subjects.

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Documento generato il 02/10/20 alle ore 01:35:56