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Titolo:
PREPULSE INHIBITION FACILITATES A LIBERAL RESPONSE BIAS IN AN AUDITORY-DISCRIMINATION TASK
Autore:
SCHALL U; WARD PB;
Indirizzi:
UNIV ESSEN GESAMTHSCH,CLIN GEN PSYCHIAT,VIRCHOWSTR 174 D-45147 ESSEN GERMANY UNIV NEW S WALES,SCH PSYCHIAT,BIOL SCHIZOPHRENIA RES TEAM,PRINCE WALES HOSP,PSYCHIAT UNIT RANDWICK NSW 2031 AUSTRALIA
Titolo Testata:
NeuroReport
fascicolo: 2, volume: 7, anno: 1996,
pagine: 652 - 656
SICI:
0959-4965(1996)7:2<652:PIFALR>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
STARTLE REFLEX; SCHIZOPHRENICS; HABITUATION; POTENTIALS;
Keywords:
PREPULSE INHIBITION; SENSORY GATING; AUDITORY DISCRIMINATION; AUDITORY MASKING; RESPONSE BIAS; CORTICAL EXCITABILITY; P300; SCHIZOPHRENIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
U. Schall e P.B. Ward, "PREPULSE INHIBITION FACILITATES A LIBERAL RESPONSE BIAS IN AN AUDITORY-DISCRIMINATION TASK", NeuroReport, 7(2), 1996, pp. 652-656

Abstract

THIS study examined 'prepulse inhibition' in the context of an auditory two-tone discrimination task performed by 15 healthy subjects. In order to distinguish between masking or excitatory information processes, weak acoustic pulses immediately preceded or succeeded a target or non-target tone in the discrimination. Button-press performance was compared with response in a no-pulse condition. Response bias (beta) became more liberal in the 100 ms prepulse and 200 ms postpulse conditions. Beta correlated with P3b amplitude measures of the event-related potential. The weak pulses increased temporarily the cortical excitability, as measured by the decreased amplitude of the P3b component and thus facilitated a more liberal response bias.

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Documento generato il 02/04/20 alle ore 06:08:43