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Titolo:
ULTRASONIC VOCALIZATION (22-28 KHZ) IN A MODEL OF CHRONIC PAIN, THE ARTHRITIC RAT - EFFECTS OF ANALGESIC DRUGS
Autore:
CALVINO B; BESSON JM; BOEHRER A; DEPAULIS A;
Indirizzi:
INSERM,U421,8 RUE GEN SARRAIL F-94010 CRETEIL FRANCE UNIV PARIS 12 CRETEIL FRANCE INSERM,U161 F-75014 PARIS FRANCE INSERM,U398 F-67085 STRASBOURG FRANCE
Titolo Testata:
NeuroReport
fascicolo: 2, volume: 7, anno: 1996,
pagine: 581 - 584
SICI:
0959-4965(1996)7:2<581:UV(KIA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADJUVANT-INDUCED ARTHRITIS; MORPHINE;
Keywords:
ULTRASONIC VOCALIZATION; ADJUVANT-INDUCED ARTHRITIS; CHRONIC PAIN; MORPHINE; ASPIRIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
B. Calvino et al., "ULTRASONIC VOCALIZATION (22-28 KHZ) IN A MODEL OF CHRONIC PAIN, THE ARTHRITIC RAT - EFFECTS OF ANALGESIC DRUGS", NeuroReport, 7(2), 1996, pp. 581-584

Abstract

ADJUVANT-induced arthritis in rats is considered as a chronic pain model. In a search for a relevant behavioural marker of the chronic painstate, we studied social interactions between an arthritic rat and a healthy partner in a neutral cage. During the test, arthritic rats emitted ultrasonic 22-28 kHz vocalizations (USV), whereas control rats did not, and showed less exploration and more immobility, but did not differ from controls in terms of social behaviours (social investigation, allogrooming). Aspirin (200 mg kg(>$($) over bar(en)1)) or morphine (3 mg kg(>$($) over bar(en)1)) injected intraperitoneally before the test significantly decreased USV without affecting the animals' behaviour. These results suggest that USV could be associated with affect related to aversive or painful stimuli and may constitute a behavioural marker of chronic pain in arthritic rats.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 14:01:52