Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ELECTROPHYSIOLOGICAL PROPERTIES OF HENSENS CELLS INVESTIGATED IN-SITU
Autore:
MAMMANO F; GOODFELLOW SJ; FOUNTAIN E;
Indirizzi:
SCH ADV INT STUDIES,BIOPHYS LAB,VIA BEIRUT 2-4 I-34014 TRIESTE ITALY UNIV BRISTOL,SCH MED SCI,DEPT PHYSIOL BRISTOL BS8 1TD AVON ENGLAND
Titolo Testata:
NeuroReport
fascicolo: 2, volume: 7, anno: 1996,
pagine: 537 - 542
SICI:
0959-4965(1996)7:2<537:EPOHCI>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
COCHLEAR HAIR-CELLS; GUINEA-PIG COCHLEA; SUPPORTING CELLS; INTRACELLULAR-RECORDINGS; ORGAN; CORTI; POTENTIALS;
Keywords:
PATCH CLAMP; FLUORESCENCE MICROSCOPY; SUPPORTING CELLS; GAP JUNCTIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
F. Mammano et al., "ELECTROPHYSIOLOGICAL PROPERTIES OF HENSENS CELLS INVESTIGATED IN-SITU", NeuroReport, 7(2), 1996, pp. 537-542

Abstract

TIGHT-SEAL whole-cell patch clamp recordings were obtained in situ from supporting Hensen's cells within the intact organ of Corti of the adult guinea pig. In normal phosphate buffer solution we estimated 20-50 cells to be coupled by gap junctions to the cell under the patch pipette. In the presence of 1 mM octanol, an uncoupling agent, it was possible to identify an outward current which activated upon depolarization above -20 mV and approached saturation above 70 mV. An inward current was seen with hyperpolarizations below -80 mV. These are broadly similar to the currents of Hensen's cells in vitro. Measured differencesof the underlying conductance indicate that the currents are sensitive to the procedure used to isolate cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 06:48:16