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Titolo:
NEURONAL DEFECTS IN GENOTYPED DOMINANT MEGACOLON (DOM) MOUSE EMBRYOS,A MODEL FOR HIRSCHSPRUNG DISEASE
Autore:
PULITI A; POIRIER V; GOOSSENS M; SIMONNEAU M;
Indirizzi:
HOP HENRI MONDOR,INSERM,U91 F-94010 CRETEIL FRANCE HOP HENRI MONDOR,INSERM,U91 F-94010 CRETEIL FRANCE HOP ROBERT DEBRE,INSERM,U120 F-7501 PARIS FRANCE
Titolo Testata:
NeuroReport
fascicolo: 2, volume: 7, anno: 1996,
pagine: 489 - 492
SICI:
0959-4965(1996)7:2<489:NDIGDM>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
AGANGLIONIC MEGACOLON; MICE; ASSOCIATION; GENE;
Keywords:
MEGACOLON; HIRSCHSPRUNG DISEASE; NEURAL CREST; ENTERIC NEURAL SYSTEM DEVELOPMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
A. Puliti et al., "NEURONAL DEFECTS IN GENOTYPED DOMINANT MEGACOLON (DOM) MOUSE EMBRYOS,A MODEL FOR HIRSCHSPRUNG DISEASE", NeuroReport, 7(2), 1996, pp. 489-492

Abstract

DOMINANT megacolon (Dom) is one of four mutations in the mouse which can produce a phenotype similar to Hirschsprung disease in man. Here, we report that it is possible to take advantage of two microsatellite markers to genotype Dom embryos and to study enteric neuronal development in Dom embryos using whole-mount immunohistochemistry. Dom embryospresent a variable defect in the ileo-caecal region, as do embryos ofother murine models of Hirschsprung disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:41:54