Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DEMENTIA AND ADULT-ONSET UNPROVOKED SEIZURES
Autore:
HESDORFFER DC; HAUSER WA; ANNEGERS JF; KOKMEN E; ROCCA WA;
Indirizzi:
COLUMBIA UNIV,GERTRUDE H SERGIEVSKY CTR,630 W 168TH ST NEW YORK NY 10032 UNIV TEXAS HOUSTON TX 00000 MAYO CLIN & MAYO FDN ROCHESTER MN 55905
Titolo Testata:
Neurology
fascicolo: 3, volume: 46, anno: 1996,
pagine: 727 - 730
SICI:
0028-3878(1996)46:3<727:DAAUS>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE; ROCHESTER; MINNESOTA; EPILEPSY; RISK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
D.C. Hesdorffer et al., "DEMENTIA AND ADULT-ONSET UNPROVOKED SEIZURES", Neurology, 46(3), 1996, pp. 727-730

Abstract

Objective: We tested the hypothesis that dementia increases the risk of unprovoked seizure among adults. Partial- and generalized-onset seizures were considered together and separately. Additionally, we explored whether the increased risk was restricted to Alzheimer's disease (AD), as previously shown. Design: Subjects in this population-based case-control study were 145 incident cases of first unprovoked seizure (without prior stroke, CNS infection, brain tumor, head trauma, mental retardation, or cerebral palsy) aged 55 years or older and 290 controlsmatched to cases on age, gender, and duration of medical follow-up. Using the records-linkage system of the Rochester Epidemiology Project,we obtained, for both cases and matched controls, information on dementia prior to onset of unprovoked seizure. Subjects were classified ashaving dementia if they met ad hoc criteria equivalent to those in the DSM-III. AD was distinguished from other dementias. Results: Both a diagnosis of AD and a diagnosis of other dementia were associated withat least a six-fold increased risk of unprovoked seizure when controlling for age, sex, and length of medical follow-up in Rochester. Therewas no difference in risk. when comparing generalized-onset seizures with partial-onset seizures. Conclusions: In the absence of other prior neurologic insult, both AD and other dementias increase the risk. ofgeneralized- and partial-onset unprovoked seizures.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 14:06:22