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Titolo:
A DINUCLEOTIDE REPEAT POLYMORPHISM AT THE GENE FOR MONOAMINE-OXIDASE-A AND MEASURES OF AGGRESSIVENESS
Autore:
VANYUKOV MM; MOSS HB; YU LM; DEKA R;
Indirizzi:
WESTERN PSYCHIAT INST & CLIN,CEDAR,3811 OHARA ST PITTSBURGH PA 15213 UNIV PITTSBURGH,DEPT PSYCHIAT,CTR EDUC & DRUG ABUSE RES PITTSBURGH PA15213 UNIV PITTSBURGH,DEPT PSYCHIAT,PITTSBURGH ADOLESCENT ALCOHOL RES CTR PITTSBURGH PA 15213 UNIV PITTSBURGH,DEPT HUMAN GENET PITTSBURGH PA 15213
Titolo Testata:
Psychiatry research
fascicolo: 1-2, volume: 59, anno: 1995,
pagine: 35 - 41
SICI:
0165-1781(1995)59:1-2<35:ADRPAT>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTISOCIAL PERSONALITY; TWINS; LOCALIZATION; BEHAVIOR; ADOPTION; PARENTS; APART;
Keywords:
GENETICS, MOLECULAR; POLYMERASE CHAIN REACTION; MICROSATELLITE POLYMORPHISM; CONDUCT DISORDER; PERSONALITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
M.M. Vanyukov et al., "A DINUCLEOTIDE REPEAT POLYMORPHISM AT THE GENE FOR MONOAMINE-OXIDASE-A AND MEASURES OF AGGRESSIVENESS", Psychiatry research, 59(1-2), 1995, pp. 35-41

Abstract

The relationship between measures of aggressiveness (personality questionnaire scales, conduct disorder diagnosis, and symptom count) and arecently discovered dinucleotide repeat length polymorphism at the monoamine oxidase type A (MAOA) gene (MAOCA-1) as a candidate locus was examined in adolescents using polymerase chain reaction. No significant correlation between aggression scales and repeat length at the MAOCA-1 marker was found, whereas the categorical diagnosis of conduct disorder showed a nonsignificant trend for an association with the marker. Alternative explanations of this trend are discussed, The data obtained suggest that the polymorphism studied is not associated with the variation in aggressiveness.

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Documento generato il 17/01/21 alle ore 04:45:08