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Titolo:
ELECTROCARDIOGRAPHIC MEASUREMENT OF INFARCT SIZE AFTER THROMBOLYTIC THERAPY
Autore:
JUERGENS CP; FERNANDES C; HASCHE ET; MEIKLE S; BAUTOVICH G; CURRIE CA; BENFREEDMAN S; JEREMY RW;
Indirizzi:
ROYAL PRINCE ALFRED HOSP,DEPT CARDIOL,MISSENDEN RD CAMPERDOWN NSW 2050 AUSTRALIA ROYAL PRINCE ALFRED HOSP,DEPT CARDIOL SYDNEY NSW AUSTRALIA ROYAL PRINCE ALFRED HOSP,DEPT NUCL MED SYDNEY NSW AUSTRALIA
Titolo Testata:
Journal of the American College of Cardiology
fascicolo: 3, volume: 27, anno: 1996,
pagine: 617 - 624
SICI:
0735-1097(1996)27:3<617:EMOISA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; QRS SCORING SYSTEM; QUANTITATIVE ANATOMIC FINDINGS; EMISSION COMPUTED-TOMOGRAPHY; CORONARY-ARTERY REPERFUSION; LEFT-VENTRICULAR FUNCTION; ST-SEGMENT ELEVATION; TL-201; PERFUSION; SINGLE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
45
Recensione:
Indirizzi per estratti:
Citazione:
C.P. Juergens et al., "ELECTROCARDIOGRAPHIC MEASUREMENT OF INFARCT SIZE AFTER THROMBOLYTIC THERAPY", Journal of the American College of Cardiology, 27(3), 1996, pp. 617-624

Abstract

Objectives. We examined the utility of the 32-point QRS score from the 12-lead electrocardiogram (EGG) for measurement of the ischemic riskregion and infarct size in patients receiving thrombolytic therapy. Background. The QRS score offers a means of evaluating the therapeutic benefit of thrombolytic therapy by comparing final infarct size with the initial extent of ischemic myocardium. Methods. The study included 38 patients (34 men, 4 women; mean [+/-SD] age 54 +/- 10 years) with afirst infarction (18 anterior, 20 inferior). The maximal potential QRS score (QRS(0)) was assigned to all leads with greater than or equal to 100-mu V ST elevation on the initial EGG. The QRS scores were calculated at 7 and 30 days after infarction. Left ventricular ejection fraction,vas measured by radionuclide ventriculography at 1 month. Twentyeight patients had thallium (TI) 201 and technetium (Tc)-99m pyrophosphate tomographic measurement of the ischemic region and infarct size. Results. The QRS(0) was 10.3 +/- 3.1 (mean +/- SD) for anterior and 10.4 +/- 3.5 for inferior infarcts. The QRS scores were similar at 7 and 30 days for both anterior (5.6 +/- 3.4 vs, 5.5 +/- 3.4) and inferiorinfarcts (3.7 +/- 2.6 vs. 2.9 +/- 2.2). The day 7 QRS score and ejection fraction at 1 month were inversely correlated (r = -0.74, p < 0.01). The Tl-201 perfusion defect was 34 +/- 11% of the left ventricle for anterior and 32 +/- 7% for inferior infarcts. Subsequent Tc-99m pyrophosphate infarct size was 15 +/- 9% of the left ventricle for anterior and 17 +/- 9% for inferior infarcts. The QRS(0) was correlated with the extent of the Tl-201 perfusion defect (r = 0.79, p < 0.001), and the day 7 QRS score was correlated with Tc-99m pyrophosphate infarct size (r = 0.79, p < 0.005). Conclusions. The 32-point QRS score can provide useful immediate measurements of the ischemic risk region and subsequent infarct size.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 21:32:48