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Titolo:
BEAM SENSORIMOTOR LEARNING AND HABITUATION TO MOTOR-ACTIVITY IN LURCHER MUTANT MICE
Autore:
LALONDE R; JOYAL CC; THIFAULT S;
Indirizzi:
HOP HOTEL DIEU,NEUROL SERV,NEUROBIOL LAB MONTREAL PQ H2W 1T8 CANADA
Titolo Testata:
Behavioural brain research
fascicolo: 1-2, volume: 74, anno: 1996,
pagine: 213 - 216
SICI:
0166-4328(1996)74:1-2<213:BSLAHT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
RABBIT;
Keywords:
LURCHER MUTANT; CEREBELLUM; MOTOR LEARNING; HABITUATION; INHIBITION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
R. Lalonde et al., "BEAM SENSORIMOTOR LEARNING AND HABITUATION TO MOTOR-ACTIVITY IN LURCHER MUTANT MICE", Behavioural brain research, 74(1-2), 1996, pp. 213-216

Abstract

Lurcher mutant mice lose cerebellar granule cells and Purkinje cells. The mutants were compared to normal mice in a beam-walking task. Normal mice were placed on a slippery bridge while lurchers, because of their severe ataxia, were placed on a bridge with the same diameter, butenveloped with surgical tape to improve traction. The performance of both groups improved with repeated trials. In an activity box, lurchermutants were as active as normal mice, showed normal intrasession habituation, and emerged from a toy object as easily as normal mice. These results indicate that the cerebellar damage in lurchers does not prevent the acquisition of a motor skill task requiring balance in an immobile apparatus. Ataxia was not accompanied by hypoactivity, inhibition or disturbances in intrasession habituation.

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Documento generato il 01/12/20 alle ore 07:46:17