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Titolo:
RESECTABILITY AND SURVIVAL IN RETROPERITONEAL SARCOMAS
Autore:
KARAKOUSIS CP; VELEZ AF; GERSTENBLUTH R; DRISCOLL DL;
Indirizzi:
SUNY BUFFALO,MILLARD FILLMORE HOSP,3 GATES CIRCLE BUFFALO NY 14209 ROSWELL PK CANC INST BUFFALO NY 14263
Titolo Testata:
Annals of surgical oncology
fascicolo: 2, volume: 3, anno: 1996,
pagine: 150 - 158
SICI:
1068-9265(1996)3:2<150:RASIRS>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
SOFT-TISSUE SARCOMAS; ABDOMINOINGUINAL INCISION; MULTIMODALITY THERAPY; PELVIC TUMORS; LIMB SALVAGE; MANAGEMENT; RESECTION;
Keywords:
RETROPERITONEAL SARCOMAS; RESECTABILITY; PROGNOSTIC FACTORS; SURVIVAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
C.P. Karakousis et al., "RESECTABILITY AND SURVIVAL IN RETROPERITONEAL SARCOMAS", Annals of surgical oncology, 3(2), 1996, pp. 150-158

Abstract

Background: Retroperitoneal sarcomas historically have presented difficulties in their management due to a high rate of unresectability, which affects the survival of these patients. Methods: We retrospectively reviewed the charts of 87 consecutive patients with retroperitoneal sarcomas treated in the period 1977-1994. Results: The resectability rate was 100% for the primary tumors (n = 55) and 87% for the locally recurrent tumors (n = 32). The 5-year survival rate was 63% (66% for the primary tumors and 57% for those with local recurrence). The 10-yearsurvival rate was 46% (57% for primary tumors and 26% for those referred with locally recurrent tumor). The overall local recurrence rate was 31% (25% for the primary tumors and 41% for those referred with local recurrence); it was 56% after local excision and 15% after wide resection (p = 0.0003). The 10-year disease-free survival of patients with local excision (n = 25) was 7%, and that of patients with wide resection (n = 54) 59% (p = 0.0001). Conclusions: The overall resectabilityrate of retroperitoneal sarcomas was 95%. Wide resection produced a significantly higher survival rate compared with that of local excision. The survival rate for the primary tumors, varying significantly withthe histologic grade, approached the rate reported for primary soft-tissue sarcomas of the extremity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:45:47