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Titolo:
INCREASE IN LECTIN-BINDING SITES ON EPITHELIAL-CELLS BY CHRONIC BLADDER INFECTION IN RATS
Autore:
NAKAGAWA T; KITAMI Y; WATANABE K; HANAI T; USUDA N; OGAWA A;
Indirizzi:
SHINSHU UNIV,SCH MED,DEPT UROL,3-1-1 ASAHI MATSUMOTO NAGANO 390 JAPAN SHINSHU UNIV,SCH MED,DEPT UROL MATSUMOTO NAGANO 390 JAPAN
Titolo Testata:
Urologia internationalis
fascicolo: 2, volume: 56, anno: 1996,
pagine: 90 - 95
SICI:
0042-1138(1996)56:2<90:IILSOE>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY-TRACT INFECTIONS; ESCHERICHIA-COLI; BACTERIAL ADHERENCE; BLOOD-GROUP; ASSOCIATION; GLYCOLIPIDS; ATTACHMENT; WOMEN;
Keywords:
LECTIN; BLADDER INFECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
T. Nakagawa et al., "INCREASE IN LECTIN-BINDING SITES ON EPITHELIAL-CELLS BY CHRONIC BLADDER INFECTION IN RATS", Urologia internationalis, 56(2), 1996, pp. 90-95

Abstract

Using lectin histochemistry we assessed whether chronic bladder infection modifies carbohydrate residues of glycoconjugates on uroepithelial cells in rats. The bladder infection was produced by implanting a knotted silk thread with Escherichia coli into the bladder. One or 4 weeks after the implantation the bladder was excised, incubated with sixteen biotinylated lectins and stained. The bladder epithelia as a wholestained more strongly positive for eight lectins in the infected ratsthan in the control rats having a sterile silk thread in the bladder. In the infected rats, the superficial epithelial layer that stained negative for Arachis hypogaea (PNA) in the controls became strongly positive for PNA, whereas the middle and deep epithelial layers increasedin staining for Canavalia ensiformis and six other lectins. These results indicate that chronic bladder infection increases carbohydrate residues on uroepithelial cells and may facilitate bacterial adherence to uroepithelial cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 05:00:58