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Titolo:
FMRI OF HUMAN SOMATOSENSORY AND CINGULATE CORTEX DURING PAINFUL ELECTRICAL NERVE-STIMULATION
Autore:
DAVIS KD; WOOD ML; CRAWLEY AP; MIKULIS DJ;
Indirizzi:
UNIV TORONTO,TORONTO HOSP,WESTERN DIV,DIV NEUROSURG,MP-14-322,399 BATHURST ST TORONTO ON M5T 2S8 CANADA UNIV TORONTO,TORONTO HOSP,WESTERN DIV,DEPT MED IMAGING TORONTO ON M5T2S8 CANADA
Titolo Testata:
NeuroReport
fascicolo: 1, volume: 7, anno: 1995,
pagine: 321 - 325
SICI:
0959-4965(1995)7:1<321:FOHSAC>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
NOXIOUS THERMAL-STIMULATION; NOCICEPTIVE NEURONS; OXYGENATION; RESPONSES; CONTRAST; MONKEYS; BRAIN;
Keywords:
FMRI; SI; CINGULATE; CORTEX; PAIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
K.D. Davis et al., "FMRI OF HUMAN SOMATOSENSORY AND CINGULATE CORTEX DURING PAINFUL ELECTRICAL NERVE-STIMULATION", NeuroReport, 7(1), 1995, pp. 321-325

Abstract

FUNCTIONAL MRI (fMRI) can detect changes from resting levels of bloodflow and oxygenation during task performance (i.e. activation). We used a simple electrical nerve stimulation technique together with fMRI to study pain processes in the human cortex. Images of the primary somatosensory (SI) and cingulate cortex (Cg) were obtained from subjects during stimulation at painful and non-painful intensities. Stimuli that evoked non-painful tingling sensations activated the contralateral SI but not Cg. Stimuli that evoked painful sensations activated both the contralateral SI and Cg. These data indicate that fMRI can detect pain-related changes in SI and Cg evoked by electrical stimulation of peripheral nerves. These findings add to the evidence for a role of SI and Cg in human pain processes and provide a simple method of stimulus delivery for its study.

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Documento generato il 09/04/20 alle ore 13:26:06