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Titolo:
LIVER METASTASES FROM GASTRIC-CARCINOMA - REPORT OF A PATIENT TREATEDWITH ADOPTIVE IMMUNOTHERAPY (TUMOR-INFILTRATING LYMPHOCYTES PLUS INTERLEUKIN-2 AND SUBSEQUENTLY LOCAL-REGIONAL LYMPHOKINE-ACTIVATED KILLER-CELLS PLUS INTERLEUKIN-2)
Autore:
FABBRI L; RIDOLFI R; RICCOBON A; MALTONI R; FLAMINI E; FEDRIGA R; FLAMIGNI A; MIGLIORI G; ORTOLANI F; CALZOLARI F; AMADORI D;
Indirizzi:
AZIENDA USL FORLI,DIV MED ONCOL,VIA FORLANINI 34 I-47100 FORLI ITALY AZIENDA USL FORLI,DIV MED ONCOL I-47100 FORLI ITALY AZIENDA USL FORLI,CTR TRASFUS FORLI ITALY AZIENDA USL FORLI,SERV RADIOL & RADIOTERAPIA FORLI ITALY IST ONCOL ROMAGNOLO FORLI ITALY
Titolo Testata:
Tumori
fascicolo: 6, volume: 81, anno: 1995,
pagine: 445 - 449
SICI:
0300-8916(1995)81:6<445:LMFG-R>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-DOSE INTERLEUKIN-2; RECOMBINANT INTERLEUKIN-2; ADVANCED CANCER; INFUSION; EXPERIENCE; TRIAL;
Keywords:
GASTRIC CANCER; INTERLEUKIN-2; LYMPHOKINE-ACTIVATED KILLER CELLS; TUMOR-INFILTRATING LYMPHOCYTES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
L. Fabbri et al., "LIVER METASTASES FROM GASTRIC-CARCINOMA - REPORT OF A PATIENT TREATEDWITH ADOPTIVE IMMUNOTHERAPY (TUMOR-INFILTRATING LYMPHOCYTES PLUS INTERLEUKIN-2 AND SUBSEQUENTLY LOCAL-REGIONAL LYMPHOKINE-ACTIVATED KILLER-CELLS PLUS INTERLEUKIN-2)", Tumori, 81(6), 1995, pp. 445-449

Abstract

A 37-year-old patient with liver metastases from gastric cancer was treated with a double adoptive immunotherapy regimen comprising tumor-infiltrating lymphocytes plus interleukin-a and subsequently local-regional lymphokine-activated killer cells plus interleukin-a because of an extremely high in vitro cytotoxic specific activity on established gastric cancer cell lines. The necrosis verified in the center of the hepatic metastasis would appear to demonstrate treatment efficacy, but no clinical response was seen. In vitro cytotoxicity data alone are insufficient to predict the clinical efficacy of adoptive immunotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 06:35:36