Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
APPLICATION OF FIRST DERIVATIVE FLUORESCENCE SPECTROMETRY TO THE SIMULTANEOUS DETERMINATION OF PARACETAMOL AND SALICYLAMIDE IN PHARMACEUTICALS
Autore:
MURILLO JA; GARCIA LF;
Indirizzi:
UNIV CASTILLA LA MANCHA,DEPT ANALYT CHEM & FOOD TECHNOL E-13071 CIUDAD REAL SPAIN
Titolo Testata:
Analytical letters
fascicolo: 3, volume: 29, anno: 1996,
pagine: 423 - 438
SICI:
0003-2719(1996)29:3<423:AOFDFS>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Keywords:
PARACETAMOL; SALICYLAMIDE; FIRST DERIVATIVE SPECTROFLUOROMETRY; SIMULTANEOUS DETERMINATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Murillo e L.F. Garcia, "APPLICATION OF FIRST DERIVATIVE FLUORESCENCE SPECTROMETRY TO THE SIMULTANEOUS DETERMINATION OF PARACETAMOL AND SALICYLAMIDE IN PHARMACEUTICALS", Analytical letters, 29(3), 1996, pp. 423-438

Abstract

The determination of paracetamol and salicylamide in the presence of each other was performed by means of a first-derivative spectrofluorimetric method with a ''zero-crossing'' technique of measurement. The reported method is based on the oxidation of the paracetamol with potassium hexacyanoferrate (III) to give a fluorescent substance. The quantitative ranges are 80-640 mu g l(-1) for paracetamol and 3.2-150.4 mu gl(-1) for salicylamide, with relative standard deviations of 3.1 and 1.3 mu g l(-1), respectively. Good results, both in terms of sensitivity and reproducibility, were obtained in the determination of paracetamol and salicylamide in the presence of each other by using this technique. The method was applied to several pharmaceutical formulations containing the drugs and was found to be satisfactory.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 16:11:29