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Titolo:
IMIPRAMINE-INDUCED INCREASE IN 5-HT2C RECEPTOR MESSENGER-RNA LEVEL INTHE RAT-BRAIN
Autore:
TOHDA M; WATANABE H;
Indirizzi:
TOYAMA MED & PHARMACEUT UNIV,RES INST WAKAN YAKU,DIV PHARMACOL SUGITANI TOYAMA 93001 JAPAN TOYAMA MED & PHARMACEUT UNIV,RES INST WAKAN YAKU,DIV PHARMACOL SUGITANI TOYAMA 93001 JAPAN
Titolo Testata:
Neuroscience research
fascicolo: 2, volume: 24, anno: 1996,
pagine: 189 - 193
SICI:
0168-0102(1996)24:2<189:III5RM>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEROTONIN-EVOKED CURRENT; XENOPUS OOCYTES; MESSENGER-RNA; 1C RECEPTOR; SELECTIVITY; DELINEATION; EXPRESSION; PROTEINS; FOS;
Keywords:
5-HT2C RECEPTOR; ANTIDEPRESSANT; DIGOXIGENIN; IN SITU HYBRIDIZATION; RAT BRAIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
M. Tohda e H. Watanabe, "IMIPRAMINE-INDUCED INCREASE IN 5-HT2C RECEPTOR MESSENGER-RNA LEVEL INTHE RAT-BRAIN", Neuroscience research, 24(2), 1996, pp. 189-193

Abstract

Repeated oral administration of 20 mg/kg imipramine elevated the level of 5-HT2C mRNA in the rat brain. Hybridization signals in nearly allregions stained by digoxigenin-labeled antisense cRNA probe, such as the hippocampus, choroid plexus, habenular nucleus, and dorsomedial hypothalamic nucleus, were more intense following imipramine treatment. These results suggest that long-term treatment with imipramine stimulates 5-HT2C receptor gene expression.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 11:43:53