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Titolo:
COMPARISON BETWEEN SUBJECTIVE FEELINGS TO ALCOHOL AND NITROGEN NARCOSIS - A PILOT-STUDY
Autore:
MONTEIRO MG; HERNANDEZ W; FIGLIE NB; TAKAHASHI E; KORUKIAN M;
Indirizzi:
ESCOLA PAULISTA MED,DEPT PSYCHOBIOL,RUA BOTUCATU 862,1 ANDAR BR-04023062 SAO PAULO BRAZIL
Titolo Testata:
Alcohol
fascicolo: 1, volume: 13, anno: 1996,
pagine: 75 - 78
SICI:
0741-8329(1996)13:1<75:CBSFTA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
SHORT-SLEEP MICE; LONG-SLEEP; GENERAL-ANESTHESIA; ETHANOL; MECHANISMS; RESPONSES; PRESSURE; MEMBRANE; SONS;
Keywords:
ETHANOL; NITROGEN NARCOSIS; GENETIC DIFFERENCES; INTOXICATION; HYPERBARIC ENVIRONMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
M.G. Monteiro et al., "COMPARISON BETWEEN SUBJECTIVE FEELINGS TO ALCOHOL AND NITROGEN NARCOSIS - A PILOT-STUDY", Alcohol, 13(1), 1996, pp. 75-78

Abstract

Nitrogen narcosis is often compared to alcohol intoxication, but no actual studies have been carried out in humans to test the comparability of these effects. If a common mechanism of action is responsible forthe behavioral effects of these substances, biological variability ofresponse to alcohol should correlate to that of nitrogen in the same individual. To test this hypothesis, subjective feelings were assessedin two separate occasions in 14 adult male, healthy volunteers, nonprofessional divers. In one occasion, each subject received 0.75 ml/kg (0.60 g/kg) alcohol 50% (v/v PO) and in another day underwent a simulated dive at 50 m for 30 min in a hyperbaric chamber. There was a significant correlation between reported feelings in the two sessions; subjects who felt less intoxicated after drinking also felt less nitrogen narcosis during the simulated dive. The results, although preliminary, raise the hypothesis that ethanol and nitrogen may share the same mechanisms of action in the brain and that biological differences might account for interindividual variability of responses to both ethanol andnitrogen.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 18:59:53