Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CORTICOTROPIN-RELEASING FACTOR AND NEUROPEPTIDE-Y - ROLE IN EMOTIONALINTEGRATION
Autore:
HEILIG M; KOOB GF; EKMAN R; BRITTON KT;
Indirizzi:
UNIV GOTEBORG,MOLNDAL HOSP,DEPT CLIN NEUROSCI,DIV PSYCHIAT S-43180 MOLNDAL SWEDEN SCRIPPS CLIN & RES INST,DEPT NEUROPHARMACOL LA JOLLA CA 92037 UNIV CALIF SAN DIEGO,VET ADM MED CTR,DEPT PSYCHIAT,PSYCHIAT SERV LA JOLLA CA 92093
Titolo Testata:
Trends in neurosciences
fascicolo: 2, volume: 17, anno: 1994,
pagine: 80 - 85
SICI:
0166-2236(1994)17:2<80:CFAN-R>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACOUSTIC STARTLE REFLEX; EXPLORATORY-BEHAVIOR; RAT-BRAIN; (NPY)-LIKE IMMUNOREACTIVITY; ANTAGONIST REVERSES; MAJOR DEPRESSION; SUICIDE VICTIMS; CONFLICT TEST; PEPTIDE-YY; AMYGDALA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
61
Recensione:
Indirizzi per estratti:
Citazione:
M. Heilig et al., "CORTICOTROPIN-RELEASING FACTOR AND NEUROPEPTIDE-Y - ROLE IN EMOTIONALINTEGRATION", Trends in neurosciences, 17(2), 1994, pp. 80-85

Abstract

The amygdala complex integrates stressful stimuli and is critical in transducing their aversive value into autonomic, endocrine and behavioural responses. Stimulation within the amygdala complex produces signsof fear without a relevant external object, while lesions in this region abolish normal fear responses. In a manner characteristic of phylogenetically old limbic brain areas, the complex neurochemical anatomy of the amygdala involves a large number of phylogenetically old peptide mediators. The distribution and connectivity of these peptide systems have been extensively studied, but less is known about their functional role. Recent evidence suggests that two neuropeptides, corticotropin-releasing factor (CRF) and neuropeptide Y (NPY) exert a reciprocal regulation of responsiveness to stressful stimuli, possibly via an interaction of these two systems in the amygdala.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 07:02:07