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Titolo:
TC-99M SESTAMIBI CARDIAC SPECT IMAGING DURING CORONARY-ARTERY OCCLUSION IN HUMANS - COMPARISON WITH DIPYRIDAMOLE STRESS STUDIES
Autore:
BORGESNETO S; WATSON JE; MILLER MJ;
Indirizzi:
DUKE UNIV,MED CTR,DEPT RADIOL,DIV NUCL MED,BOX 3949,ERWIN RD DURHAM NC 27710 VET ADM MED CTR,CARDIOL SECT CHARLESTON SC 29403
Titolo Testata:
Radiology
fascicolo: 3, volume: 198, anno: 1996,
pagine: 751 - 754
SICI:
0033-8419(1996)198:3<751:TSCSID>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION COMPUTED-TOMOGRAPHY; ACUTE MYOCARDIAL-INFARCTION; EXERCISE; DISEASE; PERFUSION; SCINTIGRAPHY; ADENOSINE;
Keywords:
CORONARY VESSELS, DISEASES; CORONARY VESSELS, RADIONUCLIDE STUDIES; DIPYRIDAMOLE; EMISSION CT (ECT), COMPARATIVE STUDIES; MYOCARDIUM, BLOOD SUPPLY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
S. Borgesneto et al., "TC-99M SESTAMIBI CARDIAC SPECT IMAGING DURING CORONARY-ARTERY OCCLUSION IN HUMANS - COMPARISON WITH DIPYRIDAMOLE STRESS STUDIES", Radiology, 198(3), 1996, pp. 751-754

Abstract

PURPOSE: To compare the magnitude of change in regional myocardial perfusion during dipyridamole stress with that during coronary occlusion. MATERIALS AND METHODS: The authors prospectively studied 14 men withmore than 50% diameter stenosis in at least one major coronary artery. Same-day rest and dipyridamole technetium-99m sestamibi single photon emission computed tomography (SPECT) was performed 24 hours before coronary angioplasty. During angioplasty, while the vessel was occluded, 15 mCi (555 MBq) of tracer was injected, and SPECT studies were obtained 60 minutes later. Extent of regional perfusion abnormalities was estimated. RESULTS: Regional perfusion defect was greater during stress and occlusion than during rest (20%, P =.001 and 14%, P =.009, respectively). SPECT defect during coronary occlusion was similar to that obtained during pharmacologic stress with dipyridamole (53% vs 47%, P =.02). CONCLUSION: Tc-99m sestamibi SPECT with dipyridamole stress is agood predictor of the extent of perfusion abnormalities that occur during coronary occlusion and may facilitate estimation of the total myocardium in jeopardy from a stenotic lesion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 09:04:09