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Titolo:
MECHANISMS OF CARCINOGENESIS AND THE MUTANT MOUSE
Autore:
WILLIAMS BO; JACKS T;
Indirizzi:
MIT,CTR CANC RES CAMBRIDGE MA 02139 MIT,HOWARD HUGHES MED INST,DEPT BIOL CAMBRIDGE MA 02139
Titolo Testata:
Current opinion in genetics & development
fascicolo: 1, volume: 6, anno: 1996,
pagine: 65 - 70
SICI:
0959-437X(1996)6:1<65:MOCATM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE INTESTINAL NEOPLASIA; WILD-TYPE P53; P53-DEFICIENT MICE; CELL-CYCLE; MUTATION; GENE; APOPTOSIS; CANCER; TUMORS; TUMORIGENESIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
71
Recensione:
Indirizzi per estratti:
Citazione:
B.O. Williams e T. Jacks, "MECHANISMS OF CARCINOGENESIS AND THE MUTANT MOUSE", Current opinion in genetics & development, 6(1), 1996, pp. 65-70

Abstract

Gene targeting in embryonic stem cells has allowed the creation of several new mouse strains carrying mutations in the murine homologs of human tumor suppressor genes. The phenotypes of these mutant strains are reviewed. In addition, recent experiments utilizing the Apc(Min) andp53 mutant animals to address specific mechanisms of carcinogenesis are discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 15:00:29