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Titolo:
PARVOVIRUS B19 INFECTION NEW PATHOPHYSIOL OGICAL PERSPECTIVES
Autore:
LABAU E; BONNET E; ALRIC L; MASSIP P;
Indirizzi:
CHU RANGUEIL,SERV PATHOL INFECT,1 AVE JEAN POULHES F-31054 TOULOUSE FRANCE CHU RANGUEIL,SERV MED INTERNE A F-31054 TOULOUSE FRANCE
Titolo Testata:
La Presse medicale
fascicolo: 4, volume: 25, anno: 1996,
pagine: 162 - 166
SICI:
0755-4982(1996)25:4<162:PBINPO>2.0.ZU;2-E
Fonte:
ISI
Lingua:
FRE
Soggetto:
INSITU HYBRIDIZATION; ARTHRITIS; HUMANS; MARROW; CELLS; DNA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
E. Labau et al., "PARVOVIRUS B19 INFECTION NEW PATHOPHYSIOL OGICAL PERSPECTIVES", La Presse medicale, 25(4), 1996, pp. 162-166

Abstract

Knowledge of the pathophysiological mechanisms governing Parvovirus B19 infection has been modified with the recent discovery of its cellular receptor. The cell lines susceptible to infection can be identifiedon the basis of the nature and distribution of the virus in the humanorganism. The Parvovirus B19 can undergo two types of cycles within the host cell. The first is a complete cycle within the infected fell leading to cell death by lysis. In the second, the cycle aborts and cell death is caused by an association of immunological phenomena and theaccumulation of viral proteins toxic to the cell. It is not known whycomplete cycles are restricted to a single erythrocyte line. These new data not only give a more precise explanation of the classical clinical expression of the disease, but also suggest possible mechanisms for the pathogenic power of the Parvovirus B19, some of which have already been proposed on the basis of clinical observations.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 04:23:08