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Titolo:
DOPPLER ASSESSMENT OF UMBILICAL FLOW AFTER GENETIC AMNIOCENTESIS
Autore:
MARTINEZ JM; COMAS C; OJUEL J; PUERTO B; BORRELL A; FORTUNY A;
Indirizzi:
C GALILEO 134 22 E-08028 BARCELONA SPAIN HOSP CLIN BARCELONA,DEPT OBSTET & GYNAECOL E-08036 BARCELONA SPAIN UNIV BARCELONA,BIOSTAT UNIT E-08036 BARCELONA SPAIN
Titolo Testata:
Early human development
fascicolo: 2, volume: 44, anno: 1996,
pagine: 105 - 111
SICI:
0378-3782(1996)44:2<105:DAOUFA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
VELOCITY WAVE-FORMS; EARLY-PREGNANCY; 1ST TRIMESTER; FETAL; UTERINE; TRIAL;
Keywords:
AMNIOCENTESIS; COLOR DOPPLER; HEMODYNAMIC EFFECTS; PRENATAL DIAGNOSIS; UMBILICAL CORD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
J.M. Martinez et al., "DOPPLER ASSESSMENT OF UMBILICAL FLOW AFTER GENETIC AMNIOCENTESIS", Early human development, 44(2), 1996, pp. 105-111

Abstract

The aim of our study was to evaluate the immediate changes on the fetal heart rate (FHR) and the fetal umbilical artery pulsatility index (UPI) after performing genetic amniocentesis. This was a prospective study including 431 consecutive singleton pregnancies between 14 and 18 weeks undergoing genetic amniocentesis in our institution. Doppler measurements were obtained transabdominally before and immediately after the procedure. Structural malformations detected by ultrasound were excluded. Student's t-test was performed for comparisons among differentgroups and observed mean changes. The results showed a significant decrease in FHR post-amniocentesis (mean 1.5 beats, t = 3.47, P < 0.01) and a non-significant elevation in UPI (mean -0.01, t = -0.29, P = 0.77) after the procedure. Differences in FHR could be found when analyzed by each gestational week. These preliminary data suggest that although acute fetal hemodynamic changes are detected after genetic amniocentesis, such changes are unlikely to have clinical relevance. However, it is reasonable to propose the use of Doppler as a method of assessing hemodynamic effects caused by prenatal invasive procedures in order to provide more accurate in vivo research on this issue.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:19:18