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Titolo:
A COMPUTERIZED APPROACH FOR MORPHOLOGICAL ANALYSIS OF THE CORPUS-CALLOSUM
Autore:
DAVATZIKOS C; VAILLANT M; RESNICK SM; PRINCE JL; LETOVSKY S; BRYAN RN;
Indirizzi:
JOHNS HOPKINS UNIV,SCH MED,DIV NEURORADIOL,600 N WOLFE ST BALTIMORE MD 21205 JOHNS HOPKINS UNIV,SCH MED,DEPT RADIOL & RADIOL SCI,NEUROIMAGING LAB BALTIMORE MD 21205 JOHNS HOPKINS UNIV,DEPT ELECT & COMP ENGN,IMAGE ANAL & COMMUN LAB BALTIMORE MD 21205 NIA,GERONTOL RES CTR,LAB PERSON & COGNIT BALTIMORE MD 21224
Titolo Testata:
Journal of computer assisted tomography
fascicolo: 1, volume: 20, anno: 1996,
pagine: 88 - 97
SICI:
0363-8715(1996)20:1<88:ACAFMA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEX-RELATED DIFFERENCES; MAGNETIC-RESONANCE; MORPHOMETRIC ANALYSIS; DIMORPHISM; HANDEDNESS; ISTHMUS; HAND;
Keywords:
IMAGE ANALYSIS; CORPUS CALLOSUM; IMAGE REGISTRATION; BRAIN, MORPHOLOGY; MAGNETIC RESONANCE IMAGERY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
C. Davatzikos et al., "A COMPUTERIZED APPROACH FOR MORPHOLOGICAL ANALYSIS OF THE CORPUS-CALLOSUM", Journal of computer assisted tomography, 20(1), 1996, pp. 88-97

Abstract

Objective: A new technique for analyzing the morphology of the corpuscallosum is presented, and it is applied to a group of elderly subjects. Materials and Methods: The proposed approach normalizes subject data into the Talairach space using an elastic deformation transformation. The properties of this transformation are used as a quantitative description of the callosal shape with respect to the Talairach atlas, which is treated as a standard. In particular, a deformation function measures the enlargement/shrinkage associated with this elastic deformation. Intersubject comparisons are made by comparing deformation functions. Results: This technique was applied to eight male and eight female subjects. Based on the average deformation functions of each group,the posterior region of the female corpus callosum was found to be larger than its corresponding region in the males. The average callosal shape of each group was also found, demonstrating visually the callosal shape differences between the two groups in this sample. Conclusion:The proposed methodology utilizes the full resolution of the data, rather than relying on global descriptions such as area measurements. The application of this methodology to an elderly group indicated sex-related differences in the callosal shape and size.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/07/20 alle ore 08:11:42