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Titolo:
TOPICAL CORTICOSTEROID-THERAPY OF RHINITIS - A REVIEW
Autore:
MYGIND N; LUND V;
Indirizzi:
RIGSHOSP,DEPT OTOLARYNGOL,OTOPATHOL LAB DK-2100 COPENHAGEN DENMARK RIGSHOSP,DEPT INTERNAL MED,ALLERGY CLIN DK-2100 COPENHAGEN DENMARK UNIV COLL LONDON,SCH MED,INST LARYNGOL & OTOL LONDON W1N 8AA ENGLAND
Titolo Testata:
CLINICAL IMMUNOTHERAPEUTICS
fascicolo: 2, volume: 5, anno: 1996,
pagine: 122 - 136
SICI:
1172-7039(1996)5:2<122:TCOR-A>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEASONAL ALLERGIC RHINITIS; AQUEOUS NASAL SPRAY; BECLOMETHASONE DIPROPIONATE AEROSOL; POSTERIOR SUBCAPSULAR CATARACTS; DAILY FLUTICASONE PROPIONATE; EOSINOPHIL CATIONIC PROTEIN; MUCOSAL MAST-CELLS; LONG-TERM SAFETY; DOUBLE-BLIND; HAY-FEVER;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
151
Recensione:
Indirizzi per estratti:
Citazione:
N. Mygind e V. Lund, "TOPICAL CORTICOSTEROID-THERAPY OF RHINITIS - A REVIEW", CLINICAL IMMUNOTHERAPEUTICS, 5(2), 1996, pp. 122-136

Abstract

The introduction of nasal corticosteroids 20 years ago has been the most important therapeutic progress in rhinitis management since the introduction of the first generation of antihistamines. Our knowledge ofthe mode of action of corticosteroids is still incomplete, although aseries of intranasal studies has now clarified this problem as the airway mucous membrane of the nose is easily accessible for investigation. Nasal corticosteroids are a highly effective therapeutic modality that can be used for long term therapy of allergic rhinitis, perennial nonallergic rhinitis and nasal polyposis. Experience for 20 years has shown that the adverse effects from this type of treatment are negligible, and far less serious than those occurring in the skin following long term use of corticosteroid ointment. Intranasal corticosteroids can therefore be considered as first-line treatment for allergic and nonallergic rhinitis. The major disadvantage of this type of treatment isthe slow onset of action and the lack of effect on itchy eyes. For that reason, the second generation antihistamines are the drugs of choice in patients having occasional symptoms. However, in our opinion, intranasal corticosteroids are preferable in patients who have symptoms on a regular basis, either in the pollen season or all year.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 20:19:54