Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE EXTRAPYRAMIDAL SYMPTOMS RATING-SCALE (ESRS) AND ITS USE IN THE EVALUATION OF RISPERIDONE
Autore:
EBERHARD G;
Indirizzi:
LUND UNIV,DEPT PSYCHIAT,POB 638 S-22009 LUND SWEDEN
Titolo Testata:
Journal of drug development and clinical practice
fascicolo: 4, volume: 7, anno: 1996,
pagine: 269 - 279
SICI:
1357-9215(1996)7:4<269:TESR(A>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLEPTIC-INDUCED AKATHISIA; TARDIVE-DYSKINESIA; SCHIZOPHRENIC PATIENTS; THERAPEUTIC REVERSAL; HALOPERIDOL; DRUGS; RATS; CHLORPROMAZINE; BENZTROPINE;
Keywords:
ESRS; EXTRAPYRAMIDAL SIDE EFFECTS; RISPERIDONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
G. Eberhard, "THE EXTRAPYRAMIDAL SYMPTOMS RATING-SCALE (ESRS) AND ITS USE IN THE EVALUATION OF RISPERIDONE", Journal of drug development and clinical practice, 7(4), 1996, pp. 269-279

Abstract

Extrapyramidal symptoms (EPS) associated with neuroleptic drug treatment include dystonia, parkinsonism, and dyskinetic movements. They arethought to be due to blockade of dopamine-D-2 receptors in the basal ganglia, and may occur in 75-90% of patients treated with conventionalneuroleptics. Systematic and reliable assessment of drug-induced movement disorders is essential, since EPS can be harmful and very distressing to the patient, often also leading to non-compliance. Several scales for rating EPS have been developed, of which the Extrapyramidal Symptoms Rating Scale (ESRS) is the most complete. The ESRS was used in multicentre trials of the serotonin-dopamine antagonist risperidone, which demonstrated consistency between the results from the ESRS and the use of antiparkinsonian medication. Together with its efficacy against the positive, negative, and affective symptoms of schizophrenia, and low incidence of EPS with standard doses, compared to conventional neuroleptics, risperidone may represent a major step forward in the care of patients with schizophrenia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 18:57:46