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Titolo:
MICROMACHINED GLUCOSE SENSOR
Autore:
STEINKUHL R; DUMSCHAT C; SUNDERMEIER C; HINKERS H; RENNEBERG R; CAMMANN K; KNOLL M;
Indirizzi:
INST CHEMO & BIOSENSORIK EV,WILHELM KLEMM STR 8 D-48149 MUNSTER GERMANY
Titolo Testata:
Biosensors & bioelectronics
fascicolo: 1-2, volume: 11, anno: 1996,
pagine: 187 - 190
SICI:
0956-5663(1996)11:1-2<187:MGS>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Keywords:
ANISOTROPIC ETCHING; CONTAINMENT SENSOR; GLUCOSE SENSOR; MASS-PRODUCTION TECHNOLOGY; MINIATURIZATION; SILICON TECHNOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
3
Recensione:
Indirizzi per estratti:
Citazione:
R. Steinkuhl et al., "MICROMACHINED GLUCOSE SENSOR", Biosensors & bioelectronics, 11(1-2), 1996, pp. 187-190

Abstract

Until now the enzyme membrane in micro-enzyme sensors has been deposited on the top of the transducer. In such sensors problems are often caused by membrane adhesion and the mechanical stability of the membrane. Furthermore, a place-selective deposition of the membrane material,which is a precondition for the development of multi-functional sensors, is difficult to achieve. To overcome these problems a new device was designed. The enzyme membrane is deposited into the chip in pyramidal containments produced on silicon by anisotropic etching. Here we demonstrate the development of glucose sensors in containment technology. Containments with opening sizes towards the analyte solution side ofbetween 120 mu m and 480 mu m were used. The enzyme membrane (gelatine gel with glucose oxidase) was deposited inside the containment. The sensitivity increased with increasing opening size. When the sensor was immersed continuously in undiluted human serum, it responded to changes in the glucose concentration for more than 2 days.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 20:17:51