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Titolo:
LYMPHOCYTIC HYPOPHYSITIS - OCCURRENCE IN 2 MEN
Autore:
LEE JH; LAWS ER; GUTHRIE BL; DINA TS; NOCHOMOVITZ LE; KOVACS KT;
Indirizzi:
GEORGE WASHINGTON UNIV,MED CTR,DEPT PATHOL,ROOM 419 ROSS HALL,2300 EYE ST NW WASHINGTON DC 20037 GEORGE WASHINGTON UNIV,MED CTR,DEPT PATHOL,ROOM 419 ROSS HALL,2300 EYE ST NW WASHINGTON DC 20037 GEORGE WASHINGTON UNIV,MED CTR,DEPT RADIOL WASHINGTON DC 20037 GEORGE WASHINGTON UNIV,MED CTR,DEPT NEUROSURG WASHINGTON DC 20037
Titolo Testata:
Neurosurgery
fascicolo: 1, volume: 34, anno: 1994,
pagine: 159 - 163
SICI:
0148-396X(1994)34:1<159:LH-OI2>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
GRANULOMATOUS HYPOPHYSITIS; CAVERNOUS SINUS; ADENOHYPOPHYSITIS; HYPOPITUITARISM; INVOLVEMENT; PREGNANCY; DISORDER; DISEASE; ENTITY;
Keywords:
GRANULOMA; HYPOPHYSITIS; LYMPHOCYTIC; PITUITARY;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
J.H. Lee et al., "LYMPHOCYTIC HYPOPHYSITIS - OCCURRENCE IN 2 MEN", Neurosurgery, 34(1), 1994, pp. 159-163

Abstract

TWO MEN UNDERGOING transsphenoidal exploration for pituitary adenoma were found to have lymphocytic hypophysitis. Both presented with frontal headaches, lethargy, and diminished libido. Laboratory investigations showed markedly depressed serum testosterone, and magnetic resonance imaging demonstrated pituitary enlargement, with optic chiasm involvement. Intraoperatively, the dura was adherent to the pituitary in each case. The resected glands were effaced by a dense lymphoplasmacytic infiltrate and fibrosis, without granulomas. Nonspecific peripheral enhancement on imaging suggested a diagnosis other than adenoma, but more experience with peripheral enhancement in lymphocytic hypophysitis is needed. The diagnosis was histological and required surgical intervention. Long-term pituitary replacement therapy is usually required.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:35:56