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Titolo:
CIRCADIAN VARIATION IN SUDDEN CARDIAC DEATH - EFFECTS OF AGE, SEX, AND INITIAL CARDIAC-RHYTHM
Autore:
THAKUR R; HOFFMANN RG; OLSON DW; JOSHI R; TRESCH DD; AUFDERHEIDE TP; IP JH;
Indirizzi:
THORAC & CARDIOVASC INST,ARRHYTHMIA SERV,405 W GREENLAWN,SUITE 110 LANSING MI 48910
Titolo Testata:
Annals of emergency medicine
fascicolo: 1, volume: 27, anno: 1996,
pagine: 29 - 34
SICI:
0196-0644(1996)27:1<29:CVISCD>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; CARDIOVASCULAR-DISEASE; ONSET; TACHYCARDIA; TIME;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
R. Thakur et al., "CIRCADIAN VARIATION IN SUDDEN CARDIAC DEATH - EFFECTS OF AGE, SEX, AND INITIAL CARDIAC-RHYTHM", Annals of emergency medicine, 27(1), 1996, pp. 29-34

Abstract

Study objective: Previous studies based on data obtained from vital statistics records have demonstrated circadian variation in the occurrence of sudden cardiac death. The purpose of this study was to examine the effects of age, sex, and initial cardiac rhythm on circadian variability in sudden cardiac death. Methods: This study employed a retrospective analysis of the records of adult patients with witnessed cardiac arrest who underwent resuscitation in an urban paramedic system during a 5-year period. Results: The records of 2,250 consecutive patientswith witnessed cardiac arrest were reviewed. Spectral analysis was used to decompose the data into frequency components. A circadian variation in the occurrence of sudden cardiac death was demonstrated, with alow occurrence rate between midnight and 6 AM and a 2.4-fold increasebetween the rate at 6 AM and the rate at noon. The same circadian pattern was noted among both men and women, among both patients aged 18 to 70 and those older than 70 years, and among patients with various initial cardiac arrest rhythms (ventricular tachycardia or fibrillation,asystole, and electromechanical dissociation). However, the outcome of resuscitation in these patients (ie, the rate of successful resuscitation and the rate of survival) did not demonstrate circadian variation. Conclusion: Witnessed out-of-hospital sudden cardiac death demonstrated circadian variation, and this variability was observed regardlessof the patient's age, sex, or initial cardiac arrest rhythm. The outcome of resuscitation did not show circadian variability. These resultssuggest a common pathophysiologic mechanism leading to sudden cardiacdeath.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 21:19:27