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Titolo:
PATENT FORAMEN OVALE - ASSOCIATION BETWEEN THE DEGREE OF SHUNT BY CONTRAST TRANSESOPHAGEAL ECHOCARDIOGRAPHY AND THE RISK OF FUTURE ISCHEMICNEUROLOGIC EVENTS
Autore:
STONE DA; GODARD J; CORRETTI MC; KITTNER SJ; SAMPLE C; PRICE TR; PLOTNICK GD;
Indirizzi:
UNIV MARYLAND HOSP,DEPT MED,DIV CARDIOL,HOMER GUDELSKY TOWER,ROOM C334,22 S GREENE ST BALTIMORE MD 21201 UNIV MARYLAND HOSP,DEPT MED,DIV CARDIOL BALTIMORE MD 21201 UNIV MARYLAND HOSP,DEPT NEUROL BALTIMORE MD 21201
Titolo Testata:
The American heart journal
fascicolo: 1, volume: 131, anno: 1996,
pagine: 158 - 161
SICI:
0002-8703(1996)131:1<158:PFO-AB>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ATRIAL SEPTAL ANEURYSM; MITRAL-VALVE PROLAPSE; PARADOXICAL EMBOLISM; CEREBRAL-ISCHEMIA; STROKE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
D.A. Stone et al., "PATENT FORAMEN OVALE - ASSOCIATION BETWEEN THE DEGREE OF SHUNT BY CONTRAST TRANSESOPHAGEAL ECHOCARDIOGRAPHY AND THE RISK OF FUTURE ISCHEMICNEUROLOGIC EVENTS", The American heart journal, 131(1), 1996, pp. 158-161

Abstract

This study investigated whether there is an association between the degree of interatrial shunting across a patent foramen ovate, as determined by saline contrast transesophageal echocardiography, and the riskof subsequent systemic embolic events, including stroke. Thirty-four patients found to have patent foramen ovate during transesophageal echocardiography were divided into two groups on the basis of the maximumnumber of microbubbles in the left heart in any single frame after intravenous saline contrast injection: group 1 (n=16) with a ''large'' degree of shunt (greater than or equal to 20 microbubbles) and group 2 (n=18) with a ''small'' degree of shunt (greater than or equal to 3 but <20 microbubbles). Patients were followed up over a mean period of 21 months for subsequent systemic embolic events, including transient ischemic attack and stroke. Five (31%) of the patients with large shunts had subsequent ischemic neurologic events, whereas none of the patients with small shunts had embolic events (p=0.03). These events occurred in spite of antiplatelet or anticoagulant therapy. We conclude thatpatients with a large degree of shunt across a patent foramen ovale, as determined by contrast transesophageal echocardiography, are at a significantly higher risk for subsequent adverse neurologic events compared with patients with a small degree of shunt.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 03:57:04