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Titolo:
THE CHANGING PROFILE OF PATIENT SELECTION, PROCEDURAL TECHNIQUES, ANDOUTCOMES IN EXCIMER-LASER CORONARY ANGIOPLASTY
Autore:
BITTL JA; BRINKER JA; SANBORN TA; ISNER JM; TCHENG JE;
Indirizzi:
BRIGHAM & WOMENS HOSP,DEPT MED,DIV CARDIOVASC,75 FRANCIS ST BOSTON MA02115
Titolo Testata:
Journal of interventional cardiology
fascicolo: 6, volume: 8, anno: 1995,
pagine: 653 - 660
SICI:
0896-4327(1995)8:6<653:TCPOPS>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPLICATIONS; DISSECTIONS; REGISTRY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Bittl et al., "THE CHANGING PROFILE OF PATIENT SELECTION, PROCEDURAL TECHNIQUES, ANDOUTCOMES IN EXCIMER-LASER CORONARY ANGIOPLASTY", Journal of interventional cardiology, 8(6), 1995, pp. 653-660

Abstract

During the course of development development of excimer excimer laserangioplasty, several changes in patient selection and technique have occurred. It is uncertain, however, whether these changes have been associated with improved procedural outcome. In this study, multivariable regression methods were used to identify the factors responsible forclinical success, major complications, and vessel perforation in 2,041 consecutive patients treated with excimer laser coronary angioplasty. The overall rates of clinical success were 89%, major complications 7.5%, and vessel perforation 2.1%. Clinical success was 86% in patients treated with prototype catheters, 89% with flexible catheters, 92% with extremely flexible catheters, and 95% in patients treated with directional eccentric catheters (P < 0.001). By multivariable analysis, clinical success increased with each subsequent catheter design (odds ratio [OR] = 1.4 per iteration [95% confidence interval 1.2, 1.6]), andwith improved lesion selection. Major complications were reduced whenoperator had performed more than 25 cases (rate = 6.5%, OR = 0.7 [0.5, 0.9]), and the incidence of vessel perforation was decreased when the size of the target vessel was > 1.0 mm larger than the diameter of the laser catheter (rate = 1.1%, OR 0.3 [0.2, 0.5]). In conclusion, during the course of clinical investigation with excimer laser angioplasty, procedural outcome has improved. These results emphasize the importance of careful patient selection and procedural technique to enhance the success of excimer laser angioplasty.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 14:44:09