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Titolo:
MAGNETIC-RESONANCE-IMAGING OF VASCULAR CHANGES IN TAKAYASU-ARTERITIS
Autore:
HATA A; NUMANO F;
Indirizzi:
TOKYO MED & DENT UNIV,SCH MED,DEPT INTERNAL MED 3,BUNKYO KU,1-5-45 YUSHIMA TOKYO 113 JAPAN
Titolo Testata:
International journal of cardiology
fascicolo: 1, volume: 52, anno: 1995,
pagine: 45 - 52
SICI:
0167-5273(1995)52:1<45:MOVCIT>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
AORTITIS SYNDROME; NATURAL-HISTORY; DISEASE;
Keywords:
MAGNETIC RESONANCE IMAGING; TAKAYASU ARTERITIS; HLA-B52; AORTIC REGURGITATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
A. Hata e F. Numano, "MAGNETIC-RESONANCE-IMAGING OF VASCULAR CHANGES IN TAKAYASU-ARTERITIS", International journal of cardiology, 52(1), 1995, pp. 45-52

Abstract

We studied the thoracic aorta in 42 female patients with Takayasu arteritis by magnetic resonance imaging (MRI) with a 1.5-T superconducting instrument and compared the findings with those in 10 healthy femalecontrols. Images in the transaxial and oblique sagittal planes were acquired by cardiac gating using a spin-echo pulse sequence. Images in the oblique plane were also obtained with cine MRI. Vascular changes were found in 41 (98%) of the patients. Dilatation of the ascending aorta was observed in 20 patients (48%), while stenotic changes were morecharacteristic in the descending aorta (16 patients, 38%). Moderate signal-intensity masses on the aortic wall were encountered in 21 patients (50%), suggesting mural thrombi. Turbulent blood flow was observedaround all masses by cine MRI. HLA analysis revealed that patients carrying HLA-B52 typing showed these masses more frequently than those without this typing (P < 0.05). Cine MRI demonstrated aortic regurgitation in 20 patients (48%), all of whom showed dilated ascending aorta; furthermore, 14 (70%) of them were confirmed as carrying HLA-B52. Thus, MRI was a useful non-invasive tool not only for the evaluation of the morphological changes in the aorta and its branches, and of the hemodynamic disturbance in Takayasu arteritis, but also for follow-up of the morbid condition.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/21 alle ore 16:39:23