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Titolo:
SIB-BASED DETECTION OF QTLS
Autore:
SUAREZ BK; HAMPE CL; OROURKE D; VANEERDEWEGH P; REICH T;
Indirizzi:
WASHINGTON UNIV,SCH MED,DEPT PSYCHIAT,4940 CHILDRENS PL ST LOUIS MO 63110 WASHINGTON UNIV,SCH MED,DEPT GENET ST LOUIS MO 63110 UNIV UTAH,DEPT ANTHROPOL SALT LAKE CITY UT 84112
Titolo Testata:
Genetic epidemiology
fascicolo: 6, volume: 12, anno: 1995,
pagine: 675 - 680
SICI:
0741-0395(1995)12:6<675:SDOQ>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
LINKAGE;
Keywords:
NONPARAMETRIC; SIB PAIR; OLIGOGENIC; QUANTITATIVE TRAIT LOCI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
5
Recensione:
Indirizzi per estratti:
Citazione:
B.K. Suarez et al., "SIB-BASED DETECTION OF QTLS", Genetic epidemiology, 12(6), 1995, pp. 675-680

Abstract

Association and transmission/nontransmission analyses were used in a split sample design to identify disease susceptibility alleles at two loci. Sib-pair analysis on various subsets of the data identified an additional four regions that yielded signals of disease predisposing quantitative trait loci (QTLs). Three of these four regions represented Type I errors. A new simulation indicates that a multiplex sampling strategy would substantially improve QTL detection for this oligogenic transmission model. (C) 1995 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 16:29:32