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Titolo:
PRESENCE OF SAUVAGINE-LIKE EPITOPES IN THE INTERRENAL GLAND OF THE BULLFROG RANA-CATESBEIANA
Autore:
GONZALEZ GC; BOUNTZIOUKAS S; LEDERIS K; LUKOWIAK K;
Indirizzi:
UNIV CALGARY,FAC MED,NEUROSCI RES GRP,3330 HOSP DR NW CALGARY AB T2N 4N1 CANADA UNIV CALGARY,FAC MED,DEPT PHARMACOL CALGARY AB T2N 4N1 CANADA
Titolo Testata:
Cell and tissue research
fascicolo: 1, volume: 283, anno: 1996,
pagine: 117 - 123
SICI:
0302-766X(1996)283:1<117:POSEIT>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICOTROPIN-RELEASING-FACTOR; FACTOR-LIKE IMMUNOREACTIVITY; CENTRAL-NERVOUS-SYSTEM; FACTOR (CRF)-LIKE IMMUNOREACTIVITY; FACTOR-CONTAINING NEURONS; UROTENSIN-I; CATOSTOMUS-COMMERSONI; ADRENAL-MEDULLA; APLYSIA-CALIFORNICA; CHROMAFFIN CELLS;
Keywords:
SAUVAGINE; CORTICOTROPIN-RELEASING FACTOR; IMMUNOCYTOCHEMISTRY; INTERRENAL GLAND; RANA CATESBEIANA (ANURA);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
G.C. Gonzalez et al., "PRESENCE OF SAUVAGINE-LIKE EPITOPES IN THE INTERRENAL GLAND OF THE BULLFROG RANA-CATESBEIANA", Cell and tissue research, 283(1), 1996, pp. 117-123

Abstract

Immunocytochemistry was used to investigate the presence of corticotropin-releasing factor-like peptides in the interrenal (adrenal) glandsof the bullfrog Rana catesbeiana by using specific antisera raised against synthetic nonconjugated rat/human corticotropin-releasing factor, urotensin I, and sauvagine. From these three antisera, covering a broad range of corticotropin-releasing factor-like immunoreactivities, only the sauvagine antiserum gave positive immunoreactivity. Sauvagine immunoreactivity was found in cortical cells grouped into cords in therenal zone of the interrenal gland. The central and subcapsular cordswere less stained. Tyrosine hydroxylase-positive chromaffin cells were not sauvagine-immunoreactive. The immunoreactivity was abolished, inall cases, by previous immuno-absorption of the sauvagine antiserum with synthetic sauvagine (0.1 mu M), but it was not eliminated by sucker (Catostomus commersoni) urotensin I, sole (Hippoglos-soides elassodon) urotensin I, sucker corticotropin-releasing factor, rat/human corticotropin-releasing factor, or ovine corticotropin-releasing factor (0.1-10 mu M). In a sauvagine radioimmunoassay, interrenal extracts displaced I-125-sauvagine from antiserum only partially, and not in parallel with the sauvagine standard curve. The results suggest that the sauvagine immunoreactivity in the R. catesbeiana interrenal gland may represent a novel sauvagine-like peptide.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 14:22:16