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Titolo:
ACTIVITY ELICITED IN THE AUDITORY PATHWAY OF THE RAT BY ELECTRICAL-STIMULATION OF THE COCHLEA
Autore:
VISCHER MW; BAJOLORENZANA V; ZHANG JS; HAUSLER R; ROUILLER EM;
Indirizzi:
UNIV BERN,INSELSPITAL,CLIN ENT HEAD & NECK SURG CH-3010 BERN SWITZERLAND
Titolo Testata:
ORL
fascicolo: 6, volume: 57, anno: 1995,
pagine: 305 - 309
SICI:
0301-1569(1995)57:6<305:AEITAP>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
C-FOS; INFERIOR COLLICULUS;
Keywords:
ELECTRICAL STIMULATION; COCHLEAR IMPLANTS; ANIMAL MODEL; AUDITORY BRAIN-STEM RESPONSES; C-FOS; COCHLEAR NUCLEUS; LATERAL LEMNISCUS; INFERIOR COLLICULUS; SINGLE UNIT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
8
Recensione:
Indirizzi per estratti:
Citazione:
M.W. Vischer et al., "ACTIVITY ELICITED IN THE AUDITORY PATHWAY OF THE RAT BY ELECTRICAL-STIMULATION OF THE COCHLEA", ORL, 57(6), 1995, pp. 305-309

Abstract

The activity elicited by electrical stimulation of the cochlea in theauditory pathway was assessed in an animal model of cochlear implantson the basis of the induction of the immediate early gene c-fos and single neuron recordings. Electrical stimulation of the cochlea inducedFos-like immunoreactivity in the cochlear nucleus, mainly in its dorsal nucleus, in the superior olivary complex, in the lateral lemniscus,but not in the central nucleus of the inferior colliculus, the main relay nucleus in the auditory midbrain. However, single unit recordingsfrom the inferior colliculus, ipsilateral and contralateral to the electrically stimulated cochlea, showed clear responses of single neurons, reminiscent of those elicited by acoustic stimulation. These findings provide immunocytochemical and electrophysiological evidence that the various nuclei of the auditory pathway are activated by electrical stimulation of the cochlea.

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Documento generato il 04/12/20 alle ore 16:18:14